Table 1

Inclusion and exclusion criteria

Inclusion criteriaExclusion criteria
Clinical

  • Age≥18 years

  • Hospitalisation with a STEMI or NSTEMI for which patient is subjected to invasive coronary angiography (within the last 6 weeks).

Clinical

  • Pregnancy.

  • Haemodynamic instability, respiratory failure or Killip class ≥3 at time of inclusion.

  • Previous CABG.

  • Indication for revascularisation by CABG.

  • Estimated life expectancy <3 year.

Angiographical

  • Patient has ≥1 non-culprit, target lesion(s) with following additional characteristics:

    • Lesion has visual stenosis of 30%–90%.

    • Lesion is non-obstructive (FFR >0.80).

    • Lesion is not in-stent restenosis.

Angiographical

  • Anatomy of target lesion(s) is unsuitable for OCT catheter crossing or imaging (aorta-ostial lesions, too small diameter segment, severe calcifications, chronic total occlusion, distal lesions prohibiting OCT imaging).

  • CABG, coronary artery bypass grafting; FFR, fractional flow reserve; NSTEMI, non-ST-elevation myocardial infarction; OCT, optical coherence tomography; STEMI, ST-elevation myocardial infarction.