Table 2

Comparison of demographic characteristics and comorbidity between vaccinated and unvaccinated groups

VariablesWithout PPSV23 vaccination n=754With PPSV23 vaccination n = 377P values
n (%)n (%)
Age (years)0.879
 75–80253 (33.6)121 (32.1)
 81–85297 (39.4)153 (40.6)
 >=86204 (27.1)103 (27.3)
Gender0.410
 Male463 (61.4)241 (63.9)
 Female291 (38.6)136 (36.1)
No. of hospitalisations for pneumonia between years 2005 and 20070.930
 0703 (93.2)356 (94.4)
 139 (5.2)17 (4.5)
 26 (0.8)3 (0.8)
 >=36 (0.8)1 (0.3)
PPSV23 vaccination period
 January−March0
 April−June0
 July−September0
 October−December377 (100)
Influenza vaccination<0.001
 Yes566 (75.1)371 (98.4)
 No188 (24.9)6 (1.6)
Influenza vaccination period0.355
 January−March6 (1.1)2 (0.5)
 April−June00
 July−September103 (18.2)57 (15.4)
 October−December457 (80.7)312 (84.1)
Chemotherapy0.251
 Yes67 (8.9)26 (6.9)
 No687 (91.1)351 (93.1)
Radiotherapy0.185
 Yes127 (16.8)52 (13.8)
 No627 (83.2)325 (86.2)
Surgery0.797
 Yes306 (40.6)156 (41.4)
 No448 (59.4)221 (58.6)
Target therapy0.082
 Yes20 (2.7)4 (1.1)
 No734 (97.3)373 (98.9)
Coronary heart disease0.038
 Yes452 (59.9)250 (66.3)
 No302 (40.1)127 (33.7)
Congestive heart failure0.375
 Yes159 (21.1)71 (18.8)
 No595 (78.9)306 (81.2)
Asthma0.279
 Yes215 (28.5)96 (25.5)
 No539 (71.5)281 (74.5)
Interstitial lung disease1.000
 Yes6 (0.8)3 (0.8)
 No748 (99.2)374 (99.2)
COPD0.141
 Yes405 (53.7)185 (49.1)
 No349 (46.3)192 (50.9)
Liver cirrhosis0.585
 Yes57 (7.6)32 (8.5)
 No697 (92.4)345 (91.5)
Diabetes mellitus0.304
 Yes312 (41.4)144 (38.2)
 No442 (58.6)233 (61.8)
Chronic renal failure (CKD)0.204
 Yes113 (15.0)46 (12.2)
 No641 (85.0)331 (87.8)
Stroke0.833
 Yes347 (46.0)171 (45.4)
 No407 (54.0)206 (54.6)
Dementia0.043
 Yes92 (12.2)31 (8.2)
 No662 (87.8)346 (91.8)
Urbanisation level0.152
 Urban226 (30.0)103 (27.3)
 Suburban281 (37.3)163 (43.2)
 Rural247 (32.8)111 (29.4)
Geographic region0.036
 North397 (52.7)176 (46.7)
 Central141 (18.7)73 (19.4)
 South195 (25.9)117 (31.0)
 East and remote islands21 (2.8)11 (2.9)
Insurance premium (NTD)0.656
 ≧30 0009 (1.2)4 (1.1)
 18 000–<30 000201 (26.7)108 (28.6)
 1–<18 000211 (28.0)113 (30.0)
 0*333 (44.2)152 (40.3)
  • *Not actively employed.

  • CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; NTD, New Taiwan Dollars; PPSV23, 23-valent pneumococcal polysaccharide vaccine.