Table 2

Median scores for patient-reported quality of life prior to treatment and at 6 months, 1 year and 2 years post-treatment with total number of patients in round brackets and 95% CIs in square brackets

Quality of lifePresurgery6 months12 months24 monthsShort term*
(baseline vs 6 months)
Long term*
(baseline vs 24 months)
Change†
(6 months vs 24 months)
EQVAS numeric‡55 [55 to 57] (4015)80 [75 to 80] (2050)80 [75 to 80] (1247)76 [75 to 80] (575)0.000↓ (2045)0.000↓ (573)0.024↑ (396)
EQ5D usual Activities1 [1 to 1] (4005)0 [0 to 0] (2051)0 [0 to 0] (1250)0 [0 to 0] (574)0.000↑ (2042)0.000↑ (570)0.477 (395)
EQ5D pain discomfort1 [1 to 1] (4004)1 [1 to 1] (2050)1 [1 to 1] (1252)1 [1 to 1] (573)0.000↑ (2041)0.000↑ (569)0.427 (394)
EQ5D anxiety depression1 [1 to 1] (3991)0 [0 to 0] (2049)0 [0 to 0] (1252)0 [0 to 0] (573)0.000↑ (2033)0.000↑ (569)0.331 (395)
EQ5D mobility0 [0 to 0] (3999)0 [0 to 0] (2046)0 [0 to 0] (1250)0 [0 to 0] (569)0.000↑ (2035)0.000↑ (563)0.339 (392)
EQ5D self-care0 [0] (3994)0 [0 to 0] (2033)0 [0 to 0] (1248)0 [0 to 0] (558)0.000↑ (2020)0.001↑ (548)0.364 (384)
EQ5D index‡§0.689 [0.689 to 0.689] (3966)0.796 [0.796 to 0.796] (2032)0.796 [0.796 to 0.796] (1245)0.796 [0.796 to 0.796] (556)0.000↓ (2010)0.000↓ (546)0.043↑ (383)
  • Median EQVAS lies in the range 0–100 with a higher score associated with a better quality of life. The other median scores (EQ5D) lie in the range 0–2, where a lower score is associated with a better quality of life.

  • Note that there is some variation in total number of responses depending on whether patients chose not to answer some questions.

  • *Statistical comparison (Mann-Whitney U test) of short-term symptom scores (6 months postsurgery) and long-term symptom scores (2 years postsurgery) with baseline scores (presurgery).

  • †Statistical comparison (Mann-Whitney U test) of change in symptom scores over time post-treatment (between 6 months and 2 years).

  • ‡A high EQVAS score or a high EQ5D index score is associated with an improvement in QoL, whereas with all other QoL and symptom scores, a low value is associated with improvement.

  • §EQ5D index of 1 is equivalent to perfect health and 0 equivalent to death. Means are reported rather than medians.

  • ↑, statistically significant increase; ↓, statistically significant decrease; EQVAS, EuroQol Visual Analogue Scale; EQ5D, EuroQol 5D; QoL, quality of life.