Gamma distribution | |||||
Disutility | SE | Alpha | Beta | Source | |
Complications or covariates | |||||
Female with type 1 diabetes and no complications | 0.0236 | 0.008 | 8.70 | 0.003 | Peasgood et al 45* |
Adverse events‡ | |||||
Severe hypoglycaemia | −0.002 | −0.002 | 1 | 0.002 | Peasgood et al 45 |
Diabetic ketoacidosis | −0.0091 | −0.01 | 0.83 | 0.01 | Peasgood et al 45* |
Nephropathy§ | |||||
Microalbuminuria | 0 | Assumption | |||
Microalbuminuria | −0.017 | 0.01 | 2.89 | 0.01 | Coffey et al 46 |
ESRD | −0.078 | 0.026 | 9 | 0.01 | Coffey et al 46 |
Neuropathy§ (applied to the history of events) | |||||
Clinical neuropathy | −0.055 | 0.01 | 30.25 | 0.002 | Coffey et al 46 |
Clinically confirmed neuropathy | −0.055 | 0.01 | 30.25 | 0.002 | Coffey et al 46 |
Diabetic foot syndrome | −0.1042 | −0.119 | 0.77 | 0.14 | Peasgood et al 45 |
PAD with amputation | −0.1172 | −0.055 | 4.54 | 0.03 | Peasgood et al 45* |
Retinopathy§ (applied to the history of events) | |||||
Background retinopathy | −0.0544 | −0.023 | 5.59 | 0.01 | Peasgood et al 45 |
Proliferative retinopathy | −0.0288 | −0.026 | 1.23 | 0.02 | Peasgood et al 45 |
Blindness | −0.208 | 0.013 | 256 | 0.001 | Coffey et al 46 |
Cardiovascular§ (applied to the history of events) | |||||
MI (first year) | −0.065 | 0.03 | 4.69 | 0.01 | Alva et al 47 |
MI (subsequent years) | −0.057 | 0.03 | 3.61 | 0.02 | Alva et al 47 |
Heart failure | −0.101 | 0.032 | 9.96 | 0.010 | Alva et al 47 |
Stroke | −0.165 | 0.035 | 22.22 | 0.007 | Alva et al 47 |
Angina | −0.09 | 0.018 | 25 | 0.004 | Clarke et al 48† |
*A parameter value was not available in the author’s preferred statistical model.
†Value is presented in table 5 as ischaemic heart disease.
‡These disutilites are applied transiently to the number of these events in each year.
§These disutilites are applied to the history of ever having had one of these events.
ESRD, end-stage renal disease; MI, myocardial infarction; PAD, peripheral arterial disease.