Score | Risk estimate | Score | Risk estimate |
−1 | 14.1 | 17 | 40.1 |
0 | 15.1 | 18 | 42.0 |
1 | 16.1 | 19 | 43.9 |
2 | 17.2 | 20 | 45.9 |
3 | 18.4 | 21 | 47.8 |
4 | 19.6 | 22 | 49.8 |
5 | 20.8 | 23 | 51.7 |
6 | 22.1 | 24 | 53.7 |
7 | 23.5 | 25 | 55.6 |
8 | 24.9 | 26 | 57.5 |
9 | 26.4 | 27 | 59.4 |
10 | 28.0 | 28 | 61.3 |
11 | 29.6 | 29 | 63.1 |
12 | 31.2 | 30 | 64.9 |
13 | 32.9 | 31 | 66.7 |
14 | 34.7 | 32 | 68.4 |
15 | 36.5 | 33 | 70.0 |
16 | 38.3 | 34 | 71.6 |
A priori risk estimate for extWML before brain MRI based on the point scoring system described in table 3. The threshold for extWML was determined by the upper quartile stratified by sex as; >6.03 cm3 for men and 4.91 cm3 for women. The point system is further described in table 3 and is based on six clinical risk factors; diastolic blood pressure (5 mm Hg increments), psychotropic drug use, antihypertensive drug use, dependence in at least one instrumental activities of daily living, self-reported forgetfulness and self-reported difficulties with simple arithmetic calculations.