Variable | n | % |
Female | 1042 | 60.8 |
Male | 672 | 39.2 |
Median age in years, IQR | 72 | 69–76 |
Married | 1013 | 59.1 |
Not married | 700 | 40.8 |
Bachelor degree | 553 | 32.3 |
Other education | 1159 | 67.6 |
BMI <25 kg/m² | 841 | 49.0 |
BMI 25–30 kg/m² | 677 | 39.5 |
BMI >30 kg/m² | 195 | 11.4 |
Median systolic BP mm Hg, IQR | 149.5 | 133–162.5 |
Median diastolic BP mm Hg, IQR | 84.5 | 77–92 |
Antihypertensive drug use | 730 | 42.6 |
Cardiovascular disease | 71 | 4.1 |
FPG ≥7.0 mmol/L | 140 | 8.2 |
Median LDL cholesterol mmol/L, IQR | 3.53 | 2.99–4.06 |
Median HDL cholesterol mmol/L, IQR | 1.61 | 1.37–1.90 |
Current tobacco smoker | 97 | 5.7 |
Former tobacco smoker | 559 | 32.6 |
Alcohol use (standard drinks per week), IQR | 7 | 1–14 |
Psychotropic drug use | 399 | 23.3 |
Depression symptoms | 221 | 12.9 |
Median MMSE score, IQR | 28 | 27–29 |
Median Benton score, IQR | 12 | 11–13 |
Total autonomy (living independently) | 1628 | 95.0 |
Dependence for at least one instrumental activity of daily living | 71 | 4.1 |
Gait imbalance | 332 | 19.4 |
Forgetfulness | 849 | 49.5 |
Difficulties retaining new simple information | 681 | 39.7 |
Difficulties with simple arithmetic calculations | 275 | 16.1 |
Difficulties with language or comprehension | 1097 | 64.0 |
MRI parameters | ||
Median no of WML, IQR | 155 | 120–197 |
Median WML volume cm3, IQR | 4.01 | 2.75–6.37 |
Median no of deep WML, IQR | 57 | 42–81 |
Median deep WML volume cm3, IQR | 1.16 | 0.75–1.79 |
Median no of periventricular WML, IQR | 95 | 74–121 |
Median periventricular WML volume cm3, IQR | 2.77 | 1.82–4.65 |
BMI, body mass index; BP, blood pressure; FPG, fasting plasma glucose; HDL, high-density lipoprotein; LDL, low-density lipoprotein; MMSE, Mini-Mental State Examination; WML, white matter lesions.