Time point | Outcome measures |
Baseline | ATRS, PSFS, SF-12 (preinjury and postinjury), VAS (pretreatment) Substudy 1: blood sample (both groups), PRP analysis (PRP group) |
2 weeks | Daily record of post-treatment pain using daily pain diary (VAS) |
6 weeks | Substudy 2: tendon needle biopsy under ultrasound guidance analysis (16 participants, 8 in each arm, central site) Immunohistochemistry analysis |
4, 7 and 13 weeks | ATRS, PSFS and SF-12 Recorded by telephone call or during outpatient visit |
24 weeks | ATRS, PSFS, SF-12, HRET Conducted via assessment at outpatient visit |
24 months | ATRS, PSFS and SF-12 recorded by telephone call |
ATRS, Achilles Tendon Rupture Score; HRET, heel-rise endurance test; PRP, platelet-rich plasma; PSFS, Patient-Specific Functional Scale; SF-12, 12-Item Short Form Health Survey; VAS, Visual Analogue Scale.