First author, year; journal | Primary objectives (to assess effect of interventions on….) | Studies details | Intervention | Outcomes (primary outcomes were in bold) ‘−': No change ‘↑': Increase ‘↓': Decrease | Synthesis methods | |||||
Educational content | Provider | Number of session(s), delivery mode, time, setting | ||||||||
Devi, 201544; The Cochrane Library | Lifestyle changes and medicines management | Number of studies: 11 completed trials (12 publications); Types of studies: RCTs; Total sample: 1392 participants | All internet-based interventions | √ BEHA (-) √ CVR (-) √ DIET (-) √ EXERCISE (-) □ MED √ PSY(-) √ SMOKING (-) □ SELF | Dietitians; exercise specialists; nurse practitioners; physiotherapist rehabilitation specialists, or did not describe. | Number of session: weekly or monthly or unclear; Total contact hours: unclear. Duration: from 6 weeks to 1 year | Strategies: internet-based and mobile phone-based intervention, such as email access, private-messaging function on the website, one-to-one chat facility, a synchronised group chat, an online discussion forum, or telephone consultations; or video files; Format: one-on-one chat sessions; ‘ask an expert’ group chat sessions; Theoretical approach: unclear | Inpatient settings, postdischarge, other | − Clinical outcomes; − Cardiovascular risk factors; − Lifestyle changes; − Compliance with medication; − Healthcare utilisation and costs; ↓ Adverse intervention effects | Meta-analysis used Review Manager software |
Barth, 201569; The Cochrane Library | Smoking cessation | Number of studies:40 RCTs; Types of studies: RCTs; Total sample: 7928 participants | Psychosocial smoking cessation interventions | □ BEHA □ CVR □ DIET □ EXERCISE □ MED □ PSY √ SMOKING □ SELF | Cardiologist; general practitioner physician or study nurse | Number of session: weekly or 2–3 times per week; Total contact hours: unclear. Duration: from 8 weeks to 1 year | Strategies: face-to-face, telephone contact, written educational materials, videotape, booklet or unclear; Format: one by one counselling; telephone call; group meetings or unclear; Theoretical approach: TTM, SCT | Inpatient settings, postdischarge, other | ↑ Abstinence by self-report or validated | Meta- analysis used Review Manager software |
Kotb, 201459; PLoS One | Patients’ outcomes | Number of studies: 26 studies; Types of studies: RCTs; Total sample: 4081 participants | Telephone-delivered postdischarge interventions | □ BEHA √ CVR □ DIET □ EXERCISE □ MED □ PSY □ SMOKING □ SELF | Dietitians; exercise specialist; health educators; nurses and pharmacists | Number of session: 3–6 sessions/telephone calls and was greater than six calls in five studies; or unclear; Total contact hours: 40 –180 mins or unclear; Duration: 1.5–6 months or unclear | Strategies: telephone calls; Format: unclear, did not describe the format; Theoretical approach: unclear | Unclear, did not describe the setting | ↓ All-cause hospitalisation; − All-cause mortality; ↓ Depression; − Anxiety; ↑ Smoking cessation, ↓ Systolic blood pressure; − LDL-c | Meta- analysis used Review Manager software |
Ghisi, 201450; Patient Education and Counseling | Knowledge, health behaviour change, medication adherence, psychosocial well-being | Number of studies: 42 articles; Types of studies: 30 were experimental: 23 RCTs and 7 quasi-experimental; and 11 observational and 1 used a mixed-methods design. Total sample: 16 079 participants | Any educational interventions | √ BEHA (+) √ CVR (++) √ DIET (+++) √ EXERCISE (++) √ MED (++) √ PSY(++) √ SMOKING (+) □ SELF | Nurses (35.7%), a multidisciplinary team (31%), dietitians (14.3%) and a cardiologist (2.4%) | Number of session: 1–24 or unclear. Total contact hours: 5–10 min to 3 hours as well as a full day of education Duration: 1–24 month; from daily education to every 6 months | Strategies: did not describe the strategies; Format: group (88.1%) education was delivered by lectures (40.5%), group discussions (40.5%) and question and answer periods (7.1%). Individual education (88.1%), including individual counselling (50%), follow-up telephone contacts (31%) and home visits (7.1%); Theoretical approach: unclear | Inpatient settings | − Knowledge; − Behaviour; − Psychosocial indicators | Narrative synthesis |
Brown, 201337; European Journal of Preventive Cardiology | Mortality, morbidity, HRQoL and healthcare costs | Number of studies: 24 papers reporting on 13 RCTs; Types of studies: RCTs; Total sample: 68 556 participants | Patient education | □ BEHA √ CVR □ DIET □ EXERCISE □ MED □ PSY □ SMOKING □ SELF | Nurses or other healthcare professionals. | Number of session and duration: from a total of 2 visits to a 4 -week residential stay reinforced with 11 months of nurse led follow-up Total contact hours: unclear | Strategies: face-to-face education sessions, telephone contact and interactive use of the internet; Format: group-based sessions, individualised education and four used a mixture of both sessions; Theoretical approach: unclear | Inpatient settings, other | − Mortality, − Non-fatal MI, − Revascularisations, − Hospitalisations, − HRQoL, − Withdrawals/dropouts; − Healthcare utilisation and costs | Meta- analysis used Review Manager software |
Dickens, 201345; Psychosomatic Medicine | Depression and depressive symptoms | Number of studies: 62 independent studies Types of studies: RCTs; Total sample: 17 397 | Psychological interventions | √ BEHA (-) □ CVR □ DIET □ EXERCISE □ MED √ PSY (-) □ SMOKING √ SELF (-) | A single health professional or by a unidisciplinary team | Number of session: 14.4 (range, 1–156); Total contact hours: varying from 10 to 240 min Duration: unclear | Strategies: face-to-face sessions, telephone contact or unclear; Format: group or unclear; Theoretical approach: unclear | Unclear, did not describe | ↓ Depression; − Adverse cardiac outcomes; − Ongoing cardiac symptoms | Univariate analyses using comprehensive meta-analysis, multivariate meta-regression using SPSS V.15.0 |
Aldcroft, 201120; Journal of Cardiopulmonary Rehabilitation & Prevention | Health behaviour change | Number of studies: seven trials Types of studies: six randomised controlled trials and a quasi-experimental trial Total sample: 536 participants | All psychoeducational or behavioural intervention | □ BEHA √ CVR (-) □ DIET □ EXERCISE □ MED √ PSY (-) □ SMOKING □ SELF | Appropriately trained healthcare workers | Number of session: unclear; Total contact hours: unclear; Duration: 2–12 months | Strategies: did not describe the strategies; Format: group setting, combination of group and one-on-one education and one-on-one format only; Theoretical approach: TTM, interactionist role theory, Bandura’s self-efficacy theory, Gordon’s relapse prevention model and a cognitive behavioural approach | Unclear, did not describe | ↓ Smoking rates; medication use; − Supplemental oxygen use; ↑ Physical activity; ↑ Nutritional habits | Meta-analysis and narrative presentation |
Brown, 201170; The Cochrane Library | Mortality, morbidity, HRQoL and healthcare costs | Number of studies: 24 papers reporting on 13 studies. Types of studies: RCTs; Total sample: 68 556 participants | Patient education | √ BEHA (-) √ CVR (-) □ DIET √ EXERCISE (-) √ MED □ PSY □ SMOKING □ SELF | Nurse or did not describe | Number of session and duration: two visits to 4 weeks residential 11 months of nurse led follow-up Total contact hours: unclear | Strategies: face-to-face sessions, telephone contact and interactive use of the internet; Format: four studies involved group sessions, five involved individualised education and three used both session types, with one study comparing the two approaches; Theoretical approach: did not describe | Postdischarge, other | − Total mortality; − Cardiovascular − mortality; − Non-cardiovascular mortality; − Total cardiovascular (CV) events; − Fatal and/or non-fatal MI; − Other fatal and/or non-fatal CV events | Meta-analysis used Review Manager software |
Goulding, 201051; Journal of Advanced Nursing | Change maladaptive illness | Number of studies: 13 studies; Types of studies: RCTs; Total sample: unclear | Interventions to change maladaptive illness beliefs | √ BEHA (-) □ CVR DIET □ EXERCISE □ MED √ PSY (-) □ SMOKING □ SELF | Cardiologist, nurse, psychologist or did not describe. | Number of session: unclear; Total contact hours: unclear; Duration: 4 days to 2 weeks or unclear | Strategies: face-to-face sessions, telephone contact and written self-administered; Format: unclear; Theoretical approach: Common Sense Model, Leventhal’s framework | Inpatient settings, postdischarge, other | − Beliefs (or other illness cognition); − QoL; − Behaviour; − Anxiety or depression; − Psychological well-being; − Modifiable risk factors; protective factors | A descriptive data synthesis |
Huttunen-Lenz, 201056; British Journal of Health Psychology | Smoking cessation | Number of studies: a total of 14 studies were included Types of studies: RCTs; Total sample: 1792 participants | Psychoeducational cardiac rehabilitation intervention | □ BEHA □ CVR □ DIET □ EXERCISE □ MED □ PSY √ SMOKING (-) □ SELF | Cardiologist, nurse psychologist or did not describe | Number of session: 4–20 or unclear. Total contact hours: 10–720 mins or unclear Duration: 4–29 weeks or unclear | Strategies: face-to-face counselling, self-help materials; home visit, booklet, video and telephone contact Format: individual or unclear Theoretical approach: social learning theory; ASE model; TTM; behavioural multicomponent approach | Inpatient settings, postdischarge, other | ↑ Prevalent smoking cessation, ↑ Continuous smoking cessation, − Mortality | Subgroup meta-analysis was used software |
Auer, 200834; Circulation | Multiple cardiovascular risk factors and all-cause mortality | Number of studies: 27 articles reporting 26 studies Types of studies: 16 clinical controlled trials and 10 before-after studies Total sample: 2467 patients in CCTs and 38, 581 patients in before-after studies | In-hospital multidimensional interventions of secondary prevention | □ BEHA □ CVR √ DIET (-) √ EXERCISE (-) √ MED √ PSY (-) √ SMOKING (-) □ SELF | Cardiac nurses; physician, or did not describe | Number of session: 1–5 or unclear; Total contact hours: 30–240 mins or unclear; Duration: 4 weeks–12 months | Strategies: Written material; audiotapes; presentations; face-to-face; Format: group or unclear; Theoretical approach: unclear | Inpatient settings | ↓ All-cause mortality; ↓ Readmission rates; − Reinfarction rates | Stata V.9.1 |
Barth, 200836; The Cochrane Library | Smoking cessation | Number of studies: 40 trials; Types of studies: RCTs; Total sample: 7682 patients | Psychosocial intervention | √ BEHA (+++) √ CVR (++) □ DIET □ EXERCISE □ MED √ PSY (+) √ SMOKING (+++) √ SELF(+++) | Cardiologist, nurse, physician or study nurse | Number of session: 1–5 or unclear; Total contact hours: 15 mins–9 hours Duration: within 4 weeks or did not report on the duration | Strategies: face-to-face; information booklets, audiotapes or videotapes Format: group sessions or individual counselling; Theoretical approach: TTM | Inpatient settings | ↑ Abstinence by self-report or validated | Meta-analysis used Review Manager software |
Fernandez, 200748; International Journal of Evidence-Based Healthcare | Risk factor modification | Number of studies: 17 trials; Types of studies: randomised, quasi-RCTs and clustered trials; Total sample: 4725 participants | Brief structured intervention | √ BEHA (-) □√ CVR (-) □ DIET □ EXERCISE □ MED □ PSY □ SMOKING √ SELF (-) | Case manager; dieticians; health educator; nurses; psychologist; and research assistants | Number of session: supportive counselling ranged from 1 to 7 calls for the duration of the study; Total contact hours: varied from 10 to 30 mins; Duration: unclear | Strategies: written, visual, audio, telephone contact; Format: did not describe; Theoretical approach: theoretical behaviour change principles | Unclear, did not describe | ↓ Smoking; − Cholesterol level; − Physical activity; ↑ Dietary habits; ↓ Blood sugar levels; − BP levels; ↓ BMI; − Incidence of admission | Cochrane statistical package Review Manager |
Barth, 200635; Annals of Behavioural Medicine | Smoking cessation | Number of studies: 19 trials; Types of studies: RCTs; Total sample: 2548 patients | Psychosocial interventions | √ BEHA (+++) √ CVR (++) □ DIET □ EXERCISE □ MED □ PSY □ SMOKING √ SELF (+++) | Unclear, did not describe | Number of session: unclear; Total contact hours: unclear; Duration: unclear | Strategies: face-to-face, telephone contact or unclear; Format: unclear; Theoretical approach: unclear | Unclear, did not describe | ↑ Abstinence; ↓ Smoking status | Data analyses were carried out in Review Manager V.4.2 |
Clark, 200541; Annals of Internal Medicine | Mortality, MI | Number of studies: 63 randomised trials; Types of studies: RCTs; Total sample: 21 295 patients | Secondary prevention programmes | □ BEHA □ CVR √ DIET (-) √ EXERCISE (-) □ MED √ PSY (-) □ SMOKING □ SELF | Nurse, multidisciplinary team or did not describe | Number of session: 1–12 or unclear Total contact hours: did not describe Duration: 0.75–48 months | Strategies: face-to-face, telephone contact and home visit; Format: group and individual or unclear; Theoretical approach: unclear | Inpatient settings, postdischarge, other | ↓ Mortality, ↓ MI, − Hospitalisation rates | Performed analyses by using Review Manager V.4.2 and Qualitative Data Synthesis |
Smoking, smoking cessation; CVR, cardiovascular risk factors; PSY, psychosocial issues (depression, anxiety); DIET, diet; EXERCISE, exercise; MED, medication; BEHA, behavioural charge (including lifestyle modification); SELF, self-management (including problems solving); DR, diabetes risks; CHD, coronary heart disease; CAD, coronary artery disease; CHW, community health worker; HbA1c, glycated haemoglobin; BP, blood pressure; LDL, low-density lipoprotein cholesterol; SMS, short message service; BCTs, behavioural change techniques; LEA, lower extremity amputation; PRIDE, Problem Identification, Researching one’s routine, Identifying a management goal, Developing a plan to reach it, Expressing one’s reactions and Establishing rewards for making progress; ASE, attitude social influence-efficacy; CVRF, cardiovascular risk factors; PA, physical activity; EDU, patient education; GP, general practice; RCTs, randomised controlled trials; CCTS, controlled clinical trials; HRQoL, health-related quality of life; QoL, quality of life; MI, myocardial infarction; CAD, coronary artery disease; CABG, coronary artery bypass graft surgery; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; HDL-c, high-density lipoprotein cholesterol; TTM, transtheoretical model; SCT, social cognitive theory; HBM, health belief model; SAT, social action theory.
In the educational content: ‘+’: minor focus; ‘++’:moderate focus; ‘+++’ major focus; ‘- ’=unclear what the intensity of the education was for any topic.
In the outcomes: arrow up (‘↑’) for improvement, arrow down (‘↓’) for reduction; a dash (‘−’) for no change or inconclusive evidence. Primary outcomes were in bold.