Summary of findings for all primary and secondary outcomes
| Study | Mortality | MI, n (%) | Stroke, n (%) | AKI, n (%) | Bleeding, n (%) | Transfusion, n (%) | ICU LOS (hour), mean (SD) | Hospital LOS (day), mean (SD) | ||||||||
| NIRS | Control | NIRS | Control | NIRS | Control | NIRS | Control | NIRS | Control | NIRS | Control | NIRS | Control | NIRS | Control | |
| Rogers et al 36 | 1 (1) | 2 (1.88) | 1 (1) | 2 (1.88) | 1 (1) | 0 | 2 (2) | 5 (4.71) | 6 (6.1) | 4 (3.77) | 37 (37.7) | 44 (45.8) | 3.3 (0.81) | 3.67 (0.79) | 7.5 (1.15) | 8 (1.17) |
| Deschamps et al 29 | 4 (11.7) | 6 (13) | 0 | 0 | 1 (2.9) | 2 (4.3) | 12 (35.2) | 17 (47.2) | – | – | – | – | 2.99 (2.26) | 0.39 (2.05) | 11 (7.2) | 9.9 (5.8) |
| Kara et al 32 | – | – | – | – | – | – | – | – | – | – | – | – | 1.74 (0.81) | 2.12 (1.05) | 7.15 (1.39) | 7.67 (1.14) |
| Colak et al 28 | – | – | 8 (8.5) | 7 (7.29) | 4 (4.25) | 1 (1) | 0 | 1 (1) | 0 | 1 (1) | 77 (81) | 73 (76) | 2.7 (6.2) | 1.9 (0.9) | - | - |
| Deschamps et al 30 | – | – | – | – | – | – | – | – | – | – | – | – | 2.99 (2.26) | 0.39 (2.05) | 7.6 (5.4) | 7.9 (3.2) |
| Vretzakis et al 35 | 1 (1.33) | 1 (1.33) | 2 (2.66) | 2 (2.66) | 1 (1.33) | 0 | 1 (1.33) | 0 | 1 (1.33) | 1 (1.33) | 51 (68) | 63 (84) | 2.7 (3.8) | 2.7 (3.6) | 10.9 (3.6) | 10.2 (10.7) |
| Mohandas et al 33 | – | – | – | – | 0 | 2 (4) | – | – | – | – | – | – | 1.49 (0.38) | 1.7 (0.49) | – | – |
| Harilall et al 31 | – | – | – | – | – | – | – | – | – | – | – | – | – | |||
| Slater et al 34 | – | – | 1 (0.8) | 1 (0.86) | 1 (0.8) | 0 | 1 (0.8) | 1 (0.86) | – | – | – | – | – | – | – | |
| Murkin et al 10 | 0 | 1 (1%) | 1 (1%) | 3 (3%) | 1 (1%) | 4 (4%) | 0 | 0 | 1 (1%) | 1 (1%) | 8 (8) | 10 (10) | 1.25 (0.84) | 1.87 (2.67) | 6.1 (4.4) | 6.9 (5.5) |
| Summary effect estimate RR (95% CI) | 0.76 (0.30 to 1.96) | 0.90 (0.43 to 1.89) | 1.08 (0.40 to 2.91) | 0.88 (0.52 to 1.49) | 1.23 (0.46 to 3.32) | 0.93 (0.77 to 1.12) | 0.00 (−0.44 to 0.44) | −0.45 (−0.90 to 0.01) | ||||||||
AKI, acute kidney injury; ICU, intensive care unit; LOS, length of stay; MI, myocardial infarction; NIRS, near-infrared spectroscopy; RR, risk ratio.