Table 2

Association between antihypertensive medications and all-cause mortality according to ethnicity

DrugAdjusted HR* (95% CI)
South AsianChineseOther
HRp ValueHRp ValueHRp Value
ACEi0.91 (0.71 to 1.17)0.470.84 (0.69 to 1.03)0.090.88 (0.84 to 0.91)<0.0001
ARB0.88 (0.63 to 1.25)0.480.64 (0.50 to 0.82)0.00040.69 (0.64 to 0.74)<0.0001
CCB1.25 (0.93 to 1.68)0.140.94 (0.77 to 1.15)0.561.00 (0.94 to 1.05)0.89
Diuretic0.83 (0.61 to 1.12)0.220.77 (0.62 to 0.96)0.020.66 (0.63 to 0.69)<0.0001
  • *Cox proportional hazards models were weighted using a propensity score model by the IPTW method adjusted for age, sex, SES, Charlson comorbidities and use of other medications (insulin, ACEi, ARB, beta-blockers, CCB, diuretics and statins) at baseline, defined as a prescription within 1 month before or after diagnosis.

  • ACEi, ACE inhibitor; ARB, angiotensin receptor blocker; CCB,  calcium channel blocker; IPTW, inverse probability of treatment weighted; SES, socioeconomic status.