Table 2

(Continued)

Patient no.	11	12	13	14	15	16	17	18	19	20
Age, years	20	47	56	46	29	33	52	32	22	53
Time since migraine onset	10 years	30 years	30 years	27 years	9 years	8 years	37 years	16 years	4 years	33 years
Time since CM onset	7 months	30 years	4 years	10 years	1 year	4 years	7 months	2 years	2 years	5 years
Aura	No	No	Visual	Visual and sensory	Visual and sensory	No	Visual and sensory	Visual	Sensory	Visual and sensory
Days per month of headache (past 3 months)	28	30	20	25	30	22	30	27	30	26
Days per month of moderate-to-severe headache (past 3 months)	15	15	12	25	15	10	20	20	5	8
Days per month of acute medication use (past 3 months)	20	30	5	25	15	20	30	0	15	8
BDI-II, score and interpretation*	6 No depression	1 No depression	8 No depression	24 Moderate depression	8 No depression	11 Mild depression	0 No depression	5 No depression	11 Mild depression	13 Mild depression
STAI-S, score and interpretation†	27 Moderate anxiety	14 Moderate anxiety	20 Moderate anxiety	30 Severe anxiery	13 Moderate anxiety	38 Severe anxiety	1 No anxiety	14 Moderate anxiety	12 No anxiety	21 Moderate anxiety
STAI-T, score and interpretation‡	23 Moderate anxiety	22 Moderate anxiety	31 Severe anxiety	39 Severe anxiety	20 Moderate anxiety	38 Severe anxiety	28 Moderate anxiety	15 No anxiety	17 Moderate anxiety	26 Moderate anxiety
Current acute medication (past 3 months)	NSAIDs Triptans	NSAIDs Triptans	Paracetamol NSAIDs	Paracetamol NSAIDs Triptans	NSAIDs Triptans	Paracetamol NSAIDs Opioids	NSAIDs Triptans	–	NSAIDs Triptans	Paracetamol NSAIDs
Prior prophylactic treatments	Magnesium	Topiramate Propranolol Flunarizine	Propranolol	Duloxetine Pregabalin	Amitriptyline	Venlafaxine	Amitriptyline	–	Amitriptyline Topiramate Nebivolol	–
Current prophylactic treatment (past 3 months)	Nebivolol Amitriptyline	Venlafaxine	Duloxetine	Topiramate	–	–	Nebivolol Zonisamide	Nebivolol Amitriptyline	–	–

*BDI-II scores: 0–9, no depression; 10–18, mild depression; 19–29, moderate depression; ≥30, severe depression (for Spanish adults).
†STAI-S scores: 0–12, no anxiety; 13–28, moderate anxiety; ≥29, severe anxiety (for Spanish adult women).
‡STAI-T scores: 0–15, no anxiety; 16–29, moderate anxiety; ≥30, severe anxiety (for Spanish adult women).
BDI-II, Beck Depression Inventory, second edition; CM, chronic migraine; NSAID, non-steroidal anti-inflammatory drugs STAI-S, State Scale of the State-Trait Anxiety Inventory; STAI-T, Trait Scale of the State-Trait Anxiety Inventory.