Characteristics of patients in the Right to Care Clinical HIV Cohort in South Africa by last treatment regimen
| Demographic characteristics | First line (N=1 10 452) | Second line (N=5909) | Third line (N=129) | |
| Gender | Female, n (%) | 70 590 (63.9) | 3822 (64.7) | 65 (50.4) |
| Male, n (%) | 39 860 (36.1) | 2087 (35.3) | 64 (49.6) | |
| Missing, n (%) | 2 (0) | 0 (0) | 0 (0) | |
| Nationality | South African, n (%) | 96 977 (88.0) | 5354 (90.6) | 109 (84.5) |
| Non-South African, n (%) | 13 176 (12.0) | 555 (9.4) | 20 (15.5) | |
| Missing, n (%) | 299 (0) | 2 (0) | 0 (0) | |
| Education level | No education, n (%) | 7372 (6.7) | 384 (6.5) | 1 (0.8) |
| Primary, n (%) | 18 520 (16.8) | 886 (15.0) | 33 (25.6) | |
| Secondary, n (%) | 56 156 (50.8) | 3058 (51.8) | 66 (51.2) | |
| Tertiary, n (%) | 2179 (2.0) | 124 (2.1) | 1 (0.8) | |
| Missing, n (%) | 26 225 (23.7) | 1457 (24.7) | 28 (21.7) | |
| Employment status | Unemployed, n (%) | 58 862 (53.3) | 3378 (57.2) | 48 (37.2) |
| Employed, n (%) | 43 261 (39.2) | 2274 (38.5) | 74 (57.4) | |
| Missing, n (%) | 8329 (7.5) | 257 (4.3) | 7 (5.4) | |
| Characteristics at ART initiation | ||||
| Age (years) | Median (IQR) | 35.6 (29.4–42.3) | 33.9 (28.4–40.1) | 36.1 (29.8–41.2) |
| Body mass index (kg/m2) | <18.5, n (%) | 12 640 (11.4) | 754 (12.8) | 14 (10.9) |
| 18.5–24.9, n (%) | 36 258 (32.8) | 1948 (33.0) | 35 (27.1) | |
| 25–29.9, n (%) | 13 289 (12.0) | 650 (11.0) | 9 (7.0) | |
| 30, n (%) | 7394 (6.7) | 340 (5.8) | 11 (8.5) | |
| Missing | 40 871 (37.0) | 2217 (37.5) | 60 (46.5) | |
| Median (IQR) | 22.2 (19.4–25.8) | 22.0 (19.1–25.3) | 22.2 (18.9–26.2) | |
| CD4 count category (cells/mm3) | <50, n (%) | 18 651 (16.9) | 1344 (22.7) | 20 (15.5) |
| 50–100, n (%) | 13 915 (12.6) | 858 (14.5) | 16 (12.4) | |
| 100–200, n (%) | 26 426 (23.9) | 1227 (20.8) | 17 (13.2) | |
| 200–350, n (%) | 17 046 (15.4) | 578 (9.8) | 15 (11.6) | |
| >350, n (%) | 7573 (6.9) | 262 (4.4) | 10 (7.8) | |
| Missing, n (%) | 26 841 (24.3) | 1640 (27.8) | 51 (39.5) | |
| Median (IQR) | 137 (58–222) | 97 (36–180) | 113 (43–257) | |
| HIV viral load (copies/mL3) | ≤1 00 000, n (%) | 17 710 (16.0) | 1100 (18.6) | 28 (21.7) |
| >1 00 000, n (%) | 10 087 (9.1) | 786 (13.3) | 12 (9.3) | |
| Missing*, n (%) | 82 655 (74.8) | 4023 (68.1) | 89 (69.0) | |
| Haemoglobin level (g/dL) | Median (IQR) | 11.5 (10.0–13.0) | 11.4 (10.0–12.8) | 11.9 (10.7–13.2) |
| Tuberculosis | Yes, n (%) | 9871 (8.9) | 632 (10.7) | 9 (6.9) |
| No, n (%) | 1 00 381 (91.1) | 5258 (89.3) | 120 (93.1) | |
| Current status | Alive and in care, n (%) | 42 542 (38.5) | 3605 (61.0) | 94 (72.9) |
| Deceased, n (%) | 10 561 (9.6) | 261 (4.4) | 2 (1.6) | |
| Lost to follow-up, n (%) | 28 561 (25.9) | 1010 (17.1) | 25 (19.4) | |
| Transferred out, n (%) | 28 788 (26.1) | 1033 (17.5) | 8 (6.2) | |
*HIV viral load was only completed at baseline in the early years of the programme.