Variables | Treatment intensified | Bivariable estimates OR (95% CI) | Multivariable estimate OR (95% CI) | ||
No | Yes | ||||
Demographics | |||||
Age (mean, SD), Year | 57 (13) | 60 (13) | 1.02 (1.00 to 1.04) | ||
Gender (n, %) | Male | 167 (80) | 41 (20) | Ref | |
Female | 241 (75) | 80 (25) | †1.35 (0.88 to 2.07) | 1.47 (0.91 to 2.37) | |
Smoking (n, %) | No | 383 (77) | 113 (23) | Ref | |
Yes | 27 (79) | 7 (21) | 0.88 (0.37 to 2.07) | ||
Alcohol use (n, %) | No | 225 (76) | 73 (25) | Ref | |
Yes | 180 (80) | 44 (20) | 0.75 (0.49 to 1.15) | ||
Marital status (n, %) | Single | 138 (77) | 42 (23) | Ref | |
Married | 269 (78) | 76 (22) | 0.93 (0.60 to 1.43) | ||
Educational status (n, %) | College/University | 82 (78) | 23 (22) | Ref | |
Secondary | 58 (70) | 25 (30) | 1.54 (0.80 to 2.97) | ||
Primary /not formal education | 262 (79) | 70 (21) | 0.95 (0.56 to 1.62) | ||
Hospital type (n, %) | Specialised | 137 (73) | 51 (27) | Ref | |
General | 280 (80) | 72 (21) | †0.69 (0.46 to 1.04) | 0.83 (0.51 to 1.37) | |
Disease characteristics (n, %) | |||||
Diabetes mellitus at current visit | No | 311 (79) | 84 (21) | Ref | |
Yes | 106 (73) | 39 (27) | †1.36 (0.88 to 2.11) | 1.10 (0.67 to 1.81) | |
Dyslipidaemia at current visit | No | 388 (77) | 113 (23) | Reference | |
Yes | 29 (74) | 10 (26) | 1.19 (0.56 to 2.50) | ||
Renal disease at current visit | No | 403 (77) | 118 (23) | Ref | |
Yes | 14 (74) | 5 (26) | 1.22 (0.43 to 3.45) | ||
Heart Failure/MI at current visit | No | 384 (77) | 112 (23) | Ref | |
Yes | 33 (75) | 11 (25) | 1.14 (0.56 to 2.33) | ||
Controlled BP at prior visit | No | 312 (77) | 96 (24) | †1.50 (0.85 to 2.66) | 1.38 (0.76 to 2.50) |
Yes | 83 (83) | 17 (17) | Ref | ||
Antihypertensive treatment characteristics | |||||
Duration of therapy years (mean SD) | 5.7 (4.1) | 8.1 (7.4) | *1.05 (1.02 to 1.08) | *1.05 (1.02 to 1.09) | |
Adherence (MMAS ≥7) (n, %) | No | 232 (76) | 73 (24) | Ref | |
Yes | 178 (78) | 49 (22) | 0.88 (0.58 to 1.32) | ||
Therapy at prior visit (n, %) | Monotherapy | 168 (76) | 53 (24) | Ref | |
Multidrug therapy | 249 (78) | 70 (22) | 0.89 (0.59 to 1.34) |
Statistically significant values: *p<0.05. Variables with *p<0.05 or †p<0.2 in the bivariable model were included in the multivariable model. Variables with a p<0.05 in the multivariable model are indicated with * and set in bold typeface. Percentages are calculated per row. Treatment intensification was calculated for 540 patients who had complete medication history (including dose and frequency) on both visits and uncontrolled BP at current visit.
BP, blood pressure; MMAS, Morisky Medication Adherence Scale; MI, myocardial infarction; Ref, reference.