Table 3

Factors associated with discontinuation of SNSF-supported RCTs

Characteristic Univariable Multivariable*
OR (95% CI) p Value OR (95% CI) p Value
Single-centre (vs multicentre)0.92 (0.37 to 2.27)0.8500.75 (0.29 to 1.94)0.559
Planned sample size (per 100 more)†0.97 (0.84 to 1.04)0.5390.96 (0.83 to 1.04)0.491
Start of RCT (per year)0.92 (0.82 to 1.03)0.1350.92 (0.82 to 1.02)0.166
  • *Complete-case multivariable logistic regression analysis (n=100) excluding one RCT with missing value for planned sample size.

  • †One missing data for planned sample size.

  • RCT, randomised clinical trial; SNSF, Swiss National Science Foundation.