Inclusion criteria | Exclusion criteria |
Age ≥18 years at time of transplant | Age ≤17 years at time of transplant |
A functioning graft* at 2 years | Failed graft before 2 years |
Renal-only transplant | Non-renal transplant |
Short-acting tacrolimus preparation | Modified release preparation at any |
Only during study period | Point during study period |
Tacrolimus as primary immunosuppressant | Other primary immunosuppressant (eg, ciclosporin, sirolimus, other non-steroid) |
Alive minimum 2 years following transplant | Pregnancy at any point during study period |
Death prior to 2 years following transplant | |
Non-standard transplant (ABO or HLA incompatible; requiring desensitisation) | |
Patients with fewer than four tacrolimus trough levels for T1 and T2 |
T1, 6–12 months post-transplant; T2, most recent 12 months.