ANCA (+) (n=49) | ANCA (−) (n=1279) | p Value | |
Number of glomeruli | 25 (20–31) | 23 (17–30) | 0.250 |
AI score | 8.31±4.36 | 6.83±4.67 | 0.023 |
Endocapillary hypercellularity | 1.61±1.17 | 1.62±1.26 | 0.972 |
Karyorrhexis/fibrinoid necrosis | 0.57±0.54 | 0.44±0.50 | 0.097 |
Cellular crescents | 1.31±1.03 | 0.85±0.85 | 0.001 |
Subendothelial hyaline deposits | 0.57±0.94 | 0.73±0.97 | 0.221 |
Glomerular leucocyte infiltration | 1.00±1.10 | 0.83±0.99 | 0.302 |
Interstitial inflammation | 1.37±0.70 | 1.08±0.67 | 0.002 |
CI score | 2.92±2.23 | 2.12±1.96 | 0.010 |
Glomerular sclerosis | 0.69±0.77 | 0.55±0.68 | 0.207 |
Tubular atrophy | 1.00±0.74 | 0.71±0.67 | 0.005 |
Fibrous crescents | 0.22±0.42 | 0.15±0.37 | 0.110 |
Interstitial fibrosis | 1.00±0.74 | 0.71±0.67 | 0.005 |
Vasculopathy | |||
Hyaline degeneration of artery | 5 (10.20) | 151 (11.81) | 0.900 |
Noninflammatory necrotising vasculopathy | 2 (4.08) | 69 (5.39) | 0.900 |
Inflammatory necrotising vasculopathy | 1 (2.04) | 2 (0.16) | 0.107 |
Thrombotic microanglopathy | 1 (2.04) | 73 (5.71) | 0.518 |
Atherosclerosis | 11 (22.45) | 434 (33.93) | 0.095 |
Values are given as n (%) or mean±SD.
AI, activity index; ANCA, anti-neutrophil cytoplasmic antibody; CI, chronicity index.