ATC class | All incidents | Incidents with probable or definite relationship with medication | Relative risk (percentages left by right column) | Swiss 2015 sales* (number of packages) | |
A | Alimentary tract and metabolism | 28 (14.6%) | 6 (15.8%) | 1.06 | 31 455 252 (14.9%) |
B | Blood and blood-forming organs | 23 (12.0%) | 7 (18.4%) | 7.08 | 5 507 624 (2.6%) |
C | Cardiovascular system | 44 (22.9%) | 1 (2.6%) | 0.35 | 16 027 143 (7.5%) |
D | Dermatologics | 1 (0.5%) | 0 (0.0%) | 0.00 | 17 314 810 (8.2%) |
G | Genitourinary system and sex hormones | 1 (0.5%) | 0 (0.0%) | 0.00 | 7 936 641 (3.7%) |
H | Systemic hormonal preparations (excluding sex hormones and insulins) | 7 (3.6%) | 1 (2.6%) | 2.00 | 2 875 760 (1.3%) |
J | Anti-infectives for systemic use | 23 (12.0%) | 6 (15.8%) | 3.95 | 8 444 623 (4.0%) |
K | Infusion liquids | 0 (0.0%) | 0 (0.0%) | 0.00 | 24 158 749 (11.5%) |
L | Antineoplastic and immunomodulating agents | 5 (2.6%) | 1 (2.6%) | 2.89 | 1 934 950 (0.9%) |
M | Musculoskeletal system | 4 (2.1%) | 2 (5.3%) | 0.76 | 14 787 413 (7.0%) |
N | Nervous system | 43 (22.4%) | 10 (26.3%) | 1.30 | 42 690 195 (20.2%) |
P | Antiparasitic products, insecticides and repellents | 1 (0.5%) | 0 (0.0%) | 0.00 | 4 62 559 (0.2%) |
R | Respiratory system | 7 (3.6%) | 3 (7.9%) | 0.57 | 28 837 468 (13.7%) |
S | Sensory organs | 2 (1.0%) | 0 (0.0%) | 0.00 | 7 658 311 (3.6%) |
T | Diagnostic use | 0 (0.0%) | 0 (0.0%) | 0.00 | 43 184 (0.0%) |
V | Various | 3 (1.6%) | 1 (2.6%) | 6.50 | 8 55 707 (0.4%) |
Total | 192 (100.0%) | 38 (100%) | 1.0 | 210 990 389 (100.0%) | |
Does not apply | 5 | 0 | n.a. | n.a. |
↵* Information by Interpharma Switzerland (see online Supplementary Appendix B).
Relative risk of drugs with probable or definite relationship with the incident as compared with sales proportions.
n.a., not available.