Table 2

Age-standardised lymphoma incidence rates (per 100 000) by WHO subtype in Manitoba, Canada (1984–2013)

Lymphoma classificationSex1984–19891990–19941995–19992000–20042005–20092010–2013
Lymphoid neoplasmsMale44.0 (41.3–46.7)50.1 (47.0–53.3)56.1 (52.8–59.4)61.2 (57.8–64.6)61.2 (57.8–64.5)62.7 (59.1–66.3)
Female34.2 (31.9–36.6)38.3 (35.7–41.0)43.7 (40.9–46.5)48.4 (45.5–51.4)47.7 (44.8–50.5)44.6 (41.6–47.6)
p Value<0.0001<0.0001<0.0001<0.0001<0.0001<0.0001
Hodgkin lymphomaMale3.8 (3.0–4.6)3.1 (2.3–3.8)2.9 (2.2–3.7)3.7 (2.8–4.5)3.6 (2.8–4.4)3.3 (2.4–4.1)
Female2.9 (2.2–3.5)2.2 (1.6– 2.9)2.3 (1.6–2.9)2.4 (1.7–3.0)2.8 (2.1–3.5)2.2 (1.5–2.8)
p Value0.0680.0990.2000.0140.1560.046
Classical Hodgkin lymphomaMale3.8 (3.0–4.5)2.8 (2.1–3.6)2.9 (2.1–3.6)3.5 (2.7–4.3)3.2 (2.5–4.0)2.9 (2.1–3.7)
Female2.8 (2.2–3.5)2.2 (1.6–2.9)2.3 (1.6–2.9)2.2 (1.6–2.8)2.7 (2–3.4)2.2 (1.5–2.8)
p Value0.0790.2380.2350.0100.3110.149
Non-Hodgkin lymphoma (NHL)Male32.5 (30.2–34.8)43.7 (40.7–46.6)50.4 (47.2–53.5)54.7 (51.5–57.9)55.8 (52.6–58.9)58.9 (54.5–61.5)
Female24.3 (22.4–26.4)32.5 (30.0–34.9)38.9 (36.3–41.6)43.7 (40.9–46.5)43.0 (40.3–45.7)40.9 (38.1–43.8)
p Value<0.0001<0.0001<0.0001<0.0001<0.0001<0.0001
Precursor NHL, B cell and T cellMale0.8 (0.5–1.2)0.7 (0.3–1.1)0.9 (0.4–1.3)0.5 (0.2–0.7)0.7 (0.3–1.1)0.9 (0.4–1.3)
Female0.6 (0.3–0.9)0.8 (0.4–1.2)0.4 (0.1–0.6)0.5 (0.2–0.7)0.6 (0.3–0.9)0.5 (0.2–0.8)
p Value0.3120.7040.0570.0520.7390.136
Mature NHL, B cellMale29.9 (27.6–32.1)36.2 (33.5–38.8)45.2 (42.3–48.2)50.4 (47.4–53.5)52.4 (49.4–55.5)54.0 (50.7–57.4)
Female22.3 (20.4–24.2)27.5 (25.2–29.7)34.9 (32.4–37.4)40.4 (37.7–43.1)40.8 (38.1–43.4)38.5 (35.8–41.3)
p Value<0.0001<0.0001<0.0001<0.0001<0.0001<0.0001
Chronic/small/prolymphocytic/mantle B cell NHLMale12.0 (10.6–13.4)11.3 (9.8–12.8)13.8 (12.2–15.5)17.4 (15.6–19.2)16.9 (15.1–18.6)15.6 (13.8–17.4)
Female6.9 (5.9–8.0)7.2 (6.1–8.4)9.6 (8.3–11.0)11.8 (10.4–13.2)11.2 (9.8–12.6)8.1 (6.8–9.4)
p Value<0.0001<0.0001<0.0001<0.0001<0.0001<0.0001
Chronic/small lymphocytic leukaemia/lymphomaMale11.8 (10.4–13.2)10.5 (9.1–11.9)12.6 (11.1–14.2)15.7 (13.9–17.4)15.2 (13.5–6.8)14.3 (12.5–15.9)
Female6.6 (5.6–7.7)6.8 (5.6–7.9)9.1 (7.8–10.3)11.2 (9.7–12.6)10.3 (8.9–11.5)7.3 (6.1–8.5)
p Value<0.0001<0.0001<0.0001<0.0001<0.0001<0.0001
Mantle cell lymphomaMale0.2 (0.0–0.3)0.8 (0.4–1.2)1.2 (0.7–1.6)1.6 (1.0–2.1)1.6 (1.1–2.2)1.4 (0.8–1.9)
Female0.3 (0.1–0.5)0.5 (0.2–0.8)0.6 (0.2–0.9)0.6 (0.3–1.0)0.9 (0.5–1.3)0.8 (0.4–1.2)
p Value0.4160.2570.0450.0060.0400.125
Lymphoplasmacytic lymphoma/WaldenstromMale0.3 (0.1–0.5)1.1 (0.6–1.5)2.1 (1.5–2.7)1.5 (1.0–2.1)1.9 (1.3–2.5)2.1 (1.4–2.7)
Female0.2 (0.0–0.4)0.6 (0.3–0.9)1.5 (1.0–2.4)1.2 (0.7–1.6)1.2 (0.7–1.7)1.4 (0.9–1.9)
p Value0.7130.1280.1560.3080.0720.124
Lymphoplasmacytic lymphomaMale0.2 (0.0–0.3)0.4 (0.1–0.6)0.4 (0.1–0.7)0.2 (0.0–0.4)0.3 (0.1–0.6)0.2 (0.0–0.4)
Female0.2 (0.0–0.3)0.1 (0.0–0.3)0.2 (0.0–0.4)0.2 (0.0–0.4)0.4 (0.1–0.6)0.2 (0.0–0.4)
p Value0.9430.1900.3520.9330.8790.949
Waldenstrom macroglobulinaemiaMale0.2 (0.0–0.3)0.7 (0.3–1.1)1.7 (1.1–2.3)1.3 (0.8–1.8)1.5 (1.0–2.1)1.8 (1.2–2.5)
Female0.2 (0.0–0.3)0.5 (0.2–0.8)1.3 (0.8–1.8)1 (0.6–1.4)0.8 (0.5–1.2)1.2 (0.7–1.7)
p Value0.6170.3420.2590.2890.0350.106
Diffuse large B cell lymphomaMale4.5 (3.6–5.3)6.5 (5.4–7.7)8.7 (7.4–10.0)9.4 (8.1–10.8)11.7 (10.2–13.1)13.5 (11.8–15.1)
Female3.4 (2.6–4.1)6.0 (4.9–7.0)7.8 (6.6–9.0)8.7 (7.5–9.9)10.9 (9.6–12.3)10.8 (9.4–12.3)
p Value0.0590.4810.2950.4370.4560.023
Follicular lymphomaMale3.9 (3.1–4.7)6.1 (5.0–7.2)7.0 (5.8–8.2)7.2 (6.0–8.4)7.1 (6.0–8.2)6.2 (5.1–7.4)
Female4.7 (3.9–5.6)5.1 (4.1–6.1)6.8 (5.7–7.9)6.1 (5.0–7.1)6.0 (5.0–7.1)6.0 (4.9–7.1)
p Value0.1870.1950.7860.1470.1780.732
Hairy cell leukaemiaMale0.8 (0.4–1.1)0.6 (0.3–1.0)1.0 (0.5–1.4)0.7 (0.3–1.0)0.7 (0.3– 1.0)0.9 (0.5–1.4)
Female0.3 (0.1–0.6)0.1 (0.0–0.3)0.2 (0.0–0.4)0.2 (0.0–0.4)0.2 (0.0–0.4)0.2 (0.0–0.5)
p Value0.0430.0250.0030.0210.0370.012
Plasma cell neoplasmsMale8.2 (7.0–9.4)9.7 (8.3–11.0)9.1 (7.8–10.5)9.2 (7.9–10.5)9.4 (8.1–10.7)10.3 (8.8–11.7)
Female6.4 (5.4–7.4)7.5 (6.4–8.7)6.5 (5.5–7.6)7.6 (6.4–8.7)7.0 (5.9–8.1)7.9 (6.6–9.1)
p Value0.0210.0210.0030.0670.0050.016
NHL, B cell, NOSMale0.1 (0.0–0.2)0.7 (0.3–1.1)1.4 (0.8–1.9)1.0 (0.6–1.5)1.1 (0.7–1.6)1.5 (1.0–2.1)
Female0.1 (0.0–0.2)0.6 (0.3–1.0)0.7 (0.3–1.0)1.2 (0.7–1.7)1.2 (0.8–1.7)1.4 (0.9–1.9)
p Value0.9600.7330.0290.5970.7210.762
Mature NHL, T cellMale0.3 (0.1–0.5)2.9 (2.1–3.6)2.2 (1.5–2.8)2.7 (2.0–3.5)2.3 (1.7–3.0)3.0 (2.2–3.8)
Female0.3 (0.1–0.5)1.4 (0.9–2.0)2.1 (1.5–2.7)1.7 (1.2–2.3)1.5 (1.0–2.0)2.0 (1.3–2.6)
p Value0.9250.0030.8600.0260.0360.039
Mycosis fungoides/Sezary syndromeMale0.0 (0.0–0.1)1.2 (0.7–1.7)0.7 (0.3–1.0)0.8 (0.4–1.2)0.8 (0.4–1.2)1.0 (0.6–1.5)
Female0.1 (0.0–0.3)0.7 (0.4–1.1)0.5 (0.2–0.8)0.5 (0.2–0.7)0.5 (0.2–0.8)0.6 (0.2–0.9)
p Value0.3640.1440.5780.1390.2050.118
Peripheral T cell lymphomaMale0.2 (0.0–0.3)1.5 (1.0–2.1)1.3 (0.8–1.8)1.6 (1.0–2.1)1.4 (0.9–1.9)1.3 (0.8–1.8)
Female0.1 (0.0–0.2)0.7 (0.3–1.0)1.3 (0.8–1.8)1.2 (0.7–1.6)0.9 (0.5–1.3)0.8 (0.4–1.2)
p Value0.3910.0110.9610.2520.1420.163
Lymphoid neoplasm, NOSMale7.7 (6.6–8.8)3.4 (2.6–4.2)2.8 (2.0–3.5)2.8 (2.1–3.6)1.7 (1.1–2.2)1.4 (0.9–2.0)
Female7.0 (5.9–8.0)3.6 (2.8–4.4)2.5 (1.8–3.2)2.4 (1.8–3.1)1.8 (1.3– 2.4)1.4 (0.9–1.9)
p Value0.3700.6750.6120.3790.7420.978
  • p Value, for the comparison between men and women based on the Mantel-Haenszel method.

  • NOS, not otherwise specified.