Groups | Controls | Screened cases | Patients with Itai-itai disease |
Number of subjects | 253 | 111 | 142 |
Mean (range) of age at baseline | 74.0 (52 to 92) | 71.5 (53 to 86) | 73.5 (52 to 91) |
Number (%) of hypertensions | 52 (20.1) | 27 (24.1) | 25 (17.7) |
Number (%) of smokers | 6 (2.4) | 3 (2.7) | 3 (2.1) |
A 26-year follow-up | |||
Number of deaths | 202 | 98 | 139 |
HR (95% CI) | 1.00 | 1.50 (1.17 to 1.91) | 2.68 (2.15 to 3.35) |
A 10-year follow-up | |||
Number of deaths | 95 | 48 | 94 |
HR (95% CI) | 1.00 | 1.60 (1.13 to 2.27) | 2.85 (2.13 to 3.80) |
Covariates, age at baseline, smoking status at present (yes: 1, no: 0) and hypertension history (yes: 1, no: 0).