Table 1

Primary outcome of four randomised free-living unsupervised home day-and-night closed-loop studies

StudyDuration of home closed loop (days)PopulationTime spent in target (%)p ValueReference
Closed loopControl
Dan04 phase 17Adolescents7253<0.001Tauschmann et al 24
Dan04 phase 221Adolescents6748<0.001Tauschmann et al 25
AP@home027Adults75630.006Leelarathna et al 23
AP@home04 phase 184Adults6857<0.001Thabit et al 10
AP@home04 phase 228Adults7666<0.001Bally et al 26