Comparison of clinical characteristics (on-admission) of dengue patients according to the presence or absence of prolonged hospital stay (>3 days)
| Variables | Total cohort (n=667) | LOS in hospital | p Value | |
| ≤3 days (n=339) | >3 days (n=328) | |||
| Age (years), mean±SD | 30.8±16.1 | 30.7±15.8 | 30.7±16.5 | 0.305 |
| Age>40 years, n (%) | 167 (25%) | 84 (24.5%) | 83 (25.3%) | 0.875 |
| Age>60 years, n (%) | 35 (5.2%) | 17 (5.1%) | 18 (5.5%) | 0.784 |
| Male gender, n (%) | 378 (56.7%) | 189 (55.8%) | 139 (42.4%) | 0.626 |
| Secondary infection, n (%) | 73 (10.9%) | 33 (9.7%) | 40 (12.2%) | 0.309 |
| Dengue severity, n (%) | ||||
| DF, n (%) | 588 (88%) | 313 (92.3%) | 275 (83.8%) | 0.001 |
| DHF*, n (%) | 79 (10.5%) | 26 (7.7%) | 53 (16.2%) | 0.001 |
| Warning signs, n (%) | 271 (40.6%) | 141 (41.6%) | 130 (39.6%) | 0.607 |
| Comorbidities, n (%) | ||||
| DM, n (%) | 36 (5.4%) | 14 (4.1%) | 22 (6.7%) | 0.141 |
| HTN, n (%) | 35 (5.2%) | 12 (3.5%) | 23 (7%) | 0.044 |
| CKD, n (%) | 33 (4.9%) | 15 (4.4%) | 18 (5.5%) | 0.522 |
| IHD, n (%) | 25 (3.7%) | 9 (2.7%) | 16 (4.9%) | 0.131 |
| Comorbidities≥2, n (%) | 36 (5.4%) | 13 (3.8%) | 23 (7%) | 0.069 |
| AKI, n (%) | 95 (14.2%) | 43 (12.7%) | 52 (15.9%) | 0.242 |
| Scr≥2 mg/dL, n (%) | 29 (4.1%) | 10 (2.9%) | 19 (5.8%) | 0.048 |
| Elevated ALT, n (%) | 362 (54.3%) | 192 (56.6%) | 170 (51.8%) | 0.197 |
| Elevated AST, n (%) | 447 (67%) | 226 (66.7%) | 221 (67.4%) | 0.636 |
| Elevated ALP, n (%) | 133 (19.9%) | 44 (13%) | 89 (27.1%) | <0.001 |
| Prolonged PT, n (%) | 224 (33.3%) | 80 (23.6%) | 144 (43.9%) | <0.001 |
| Prolonged aPTT, n (%) | 159 (23.8%) | 52 (15.3%) | 107 (32.6%) | <0.001 |
| Thrombocytopenia, n (%) | 395 (59.2%) | 191 (56.3%) | 204 (62.2%) | 0.134 |
| MODs, n (%) | 117 (17.5%) | 44 (13%) | 72 (22.3%) | 0.002 |
| Haematocrit>20%, n (%) | 73 (10.9%) | 38 (11.2%) | 35 (10.7%) | 0.824 |
p values were calculated between patients with and without prolonged hospital stay.
*DHF includes all four grades.
AKI, acute kidney injury; ALP, alkaline phosphatase; ALT, alanine aminotransferase; aPTT, activated partial thromboplastin time; AST, aspartate aminotransferase; CKD, chronic kidney disease; DF, dengue fever; DHF, dengue haemorrhagic fever; DM, diabetes mellitus; HTN, hypertension; IHD, ischaemic heart disease; LOS, length of stay; MODs, multiple organ dysfunction; PT, prothrombin time; Scr, serum creatinine.