Data table of principle of paired design for the faecal markers calprotectin and calgranulin C
| Faecal calgranulin C | ||||
| Positive | Negative | Total | ||
| Diagnosis: no IBD | ||||
| Faecal calprotectin | Positive | Concordant (v) | Discordant (w) | v+w |
| Negative | Discordant (x) | Concordant (y) | x+y | |
| Total | v+x | w+y | N− | |
| Diagnosis: IBD | ||||
| Faecal calprotectin | Positive | Concordant (r) | Discordant (s) | r+s |
| Negative | Discordant (t) | Concordant (u) | t+u | |
| Total | r+t | s+u | N+ | |
Null hypothesis H0 (specificity): w=x; alternative hypothesis H1: w≠x.
Null hypothesis H0 (sensitivity): s=t; alternative hypothesis H1: s≠t.
IBD, inflammatory bowel disease.