Schedule of assessments at baseline and post intervention
| Measures | Baseline | Post intervention |
| Tumour morphology (off-site) | ||
| MRI scan: T1-axial | X | X |
| Tumour biomarkers | ||
| Blood: HIF-1α, TGF-β | X | X |
| Anthropometry | ||
| Height (cm) | X | |
| Weight (kg) | X | X |
| Waist circumference (cm) | X | X |
| Hip circumference (cm) | X | X |
| Femoral length (mm) | X | |
| Tibial length (mm) | X | |
| Body mass index (kg/m2) | X | X |
| Waist-to-hip ratio | X | X |
| Body composition | ||
| DXA scans: whole-body, spinal, hip | X | X |
| pQCT scans: femoral, tibial | X | X |
| Physical assessments | ||
| NeuroCom Balance test | X | X |
| 1RM Strength test (leg extension) | X | X |
| 400m walk test | X | X |
| Timed Up and Go test | X | X |
| Other biomarkers (off-site) | ||
| Blood: P1NP, ALP, CRP, fasting glucose and lipids, PSA | X | X |
| Urine: NTx | X | X |
| Questionnaires | ||
| Demographic and health history | X | |
| Concomitant medications | X | X |
| Health-related Quality of Life (SF-36) | X | X |
| Cancer-specific Quality of Life (EORTC: QLQ30, PR25) | X | X |
| Brief Symptom Index (BSI-18) | X | X |
| Insomnia Severity Index | X | X |
| Godin Leisure-Time Exercise | X | X |
| Exercise programme | ||
| Clinic exercise record sheet (prescribed vs actual) | At each exercise session | |
| Home exercise record sheet (prescribed vs actual) | At each exercise session | |
ALP, alkaline phosphate; CRP, C reactive protein; DXA, dual-energy X-ray absorptiometry; EORTC, European Organisation for Research and Treatment of Cancer; HIF-1α, hypoxia-inducible factor 1-alpha; NTx, amino-terminal collagen type 1 telopeptide; P1NP, amino-terminal propeptide of type 1 procollagen; pQCT, peripheral quantitative CT; PSA, prostate-specific antigen; SF-36, short form-36; TGF-β, transformation growth-like factor beta.