Planned inclusion and exclusion criteria
| Inclusion criteria | Exclusion criteria | |
| Population | Adult patients (>18 years) with a tremor diagnosis of confirmed aetiology Unilateral or bilateral lesional functional neurosurgical intervention in a central neuroanatomical structure By incisional (placement of a stylette, leukotome, cryosurgery or radiofrequency probe after skull opening) or incision-less (transcranially focused ultrasound (MRI-guided focused ultrasound), radiation energy (Gamma Knife) means | Cases subjected to lesional functional neurosurgery in more than one anatomical structure at the same time Or stimulation techniques (deep brain stimulation) |
| Study design | Randomised controlled trials, meta-analysis, case-control, prospective and retrospective case series A minimum of five subjects included per cohort (indication/treatment) Minimum follow-up of 2 months after the intervention | Studies reporting results from mixed aetiologies or mixed intervention (different anatomical targets or techniques) |
| Efficacy outcome | Reporting tremor outcome on a validated tremor scale | |
| Safety outcome | Side effects after unilateral only interventions | Cohorts including bilateral interventions |
| Type of publication | Peer-reviewed articles without language restriction | Letters, abstracts and editorials |