Baseline characteristics of participants
| CON group n=35 | AT group n=35 | |
|---|---|---|
| Variables at baseline | Mean (SD) or n (%) or median (IQR) | Mean (SD) or n (%) or median (IQR) |
| Descriptive variables and covariates | ||
| Age, years | 73.7 (8.3) | 74.8 (8.4) |
| Gender, female | 17 (49%) | 19 (54%) |
| Education, >high school | 27 (82%) | 24 (69%) |
| Functional Comorbidity Index | 2.8 (2.2) | 2.8 (1.5) |
| Hypertensive, yes | 20 (61%) | 17 (49%) |
| Mini-mental state examination | 26.4 (3.1) | 26.3 (2.7) |
| Montreal cognitive assessment | 21.7 (4.4) | 20.7 (3.3) |
| Waist-to-hip ratio | 0.93 (0.07) | 0.88 (0.08) |
| Short physical performance battery | 10.51 (1.20) | 10.62 (1.86) |
| Time-up-and-go (s) | 8.67 (2.26) | 8.82 (2.36) |
| Physiological profile assessment | 0.94 (1.42) | 0.94 (1.39) |
| Medications | ||
| Taking beta blockers, yes | 7 (20%) | 7 (20%) |
| Central-effecting medications, no | 0.5 (1.0) | 0.6 (0.9) |
| Total medications, no | 4.2 (3.4) | 3.5 (2.7) |
| Primary clinical and economic outcome variables | ||
| Alzheimer's disease assessment scale, cognition | 10.2 (5.4) | 11.7 (5.5) |
| Executive interview | 13.3 (6.4) | 13.7 (4.7) |
| ADCS-ADL | 46.5 (5.1) | 46.1 (6.8) |
| EQ-5D-3L (patient rated) | 0.797 (0.109) 0.817 (0.135) | 0.822 (0.072) 0.826 (0.108) |
| EQ-5D-3L (caregiver rated) | 0.799 (0.136) 0.826 (0.117) | 0.829 (0.064) 0.843 (0.108) |
| Secondary outcome variables | ||
| Stroop Test 3-2 (s) | 57.12 (24.13) | 67.82 (28.36) |
| Trail making test B-A (s) | 75.18 (83.27) | 59.70 (42.28) |
| Digit span forward—backward | 3.8 (1.95) | 3.37 (2.44) |
| 6-minute walk (m) | 486.9 (97.9) | 502.8 (98.4) |
| Weight (kg) | 72.39 (14.11) | 70.05 (14.31) |
| Body mass index | 26.54 (3.97) | 25.26 (3.54) |
| Resting heart rate (bpm) | 70.24 (15.10) | 67.26 (12.38) |
| Resting systolic blood pressure (mm Hg) | 132.29 (18.66) | 139.80 (17.73) |
| Resting diastolic blood pressure (mm Hg) | 76.71 (11.38) | 80.26 (10.05) |
| Physical activity scale for the elderly | 118.59 (55.41) | 124.44 (73.47) |
AT, aerobic exercise training group; CON, nutrition education.