Finding | 45–54 years | 95% CI | 55–64 years | 95% CI | 65–75 years | 95% CI |
---|---|---|---|---|---|---|
(n=211) | (n=245) | (n=119) | ||||
White matter hyperintensities, n (%)* | 7 (3.32) | (1.64 to 6.68) | 21 (8.57) | (5.68 to 12.75) | 17 (14.29) | (9.13 to 21.71) |
Vascular abnormalities* | ||||||
Lacunar infarct, n (%)* | 2 (0.95) | (0.29 to 3.36) | 6 (2.45) | (1.15 to 5.23) | 8 (6.72) | (3.48 to 12.71) |
Microhaemorrhage, n (%)* | 0 | – | 5 (2.04) | (0.90 to 4.67) | 4 (3.36) | (1.36 to 8.31) |
Single cavernous malformation, n (%) | 2 (0.95) | (0.29 to 3.36) | 8 (3.26) | (1.6 to 6.30) | 4 (3.36) | (1.36 to 8.31) |
Malformation of venous development, n (%) | 9 (4.26) | (2.28 to 7.90) | 10 (4.08) | (2.25 to 7.37) | 1 (0.84) | (0.20 to 4.55) |
Neoplasias | ||||||
Meningioma, n (%) | 3 (1.42) | (0.51 to 4.07) | 5 (2.04) | (0.90 to 4.67) | 2 (1.68) | (0.52 to 5.89) |
Pituitary mass, n (%) | 0 | – | 2 (0.82) | (0.25 to 2.90) | 0 | – |
Small intraventricular mass,† n (%) | 1 (0.47) | (0.11 to 2.60) | 0 | – | 0 | – |
Cerebellar hemispheric mass, n (%) | 0 | – | 1 (0.41) | (0.09 to 2.24) | 0 | – |
Brain volume loss* | ||||||
Frontal, n (%)* | 0 | – | 1 (0.41) | (0.90 to 2.24) | 7 (5.88) | (2.92 to 11.64) |
Temporal, n (%)* | 2 (0.95) | (0.29 to 3.36) | 2 (0.82) | (0.25 to 2.90) | 4 (3.36) | (1.36 to 8.31) |
Parietal, n (%)* | 2 (0.95) | (0.29 to 3.36) | 2 (0.82) | (0.25 to 2.90) | 4 (3.36) | (1.36 to 8.31) |
Cerebellum and brain stem, n (%) | 1 (0.47) | (0.11 to 2.60) | 1 (0.41) | (0.90 to 2.24) | 2 (1.68) | (0.52 to 5.89) |
Diffuse loss of brain volume, n (%)* | 1 (0.47) | (0.11 to 2.60) | 4 (1.63) | (0.66 to 4.11) | 8 (6.72) | (3.48 to 12.71) |
*Statistically significant positive correlation with increasing age (r, p<0.005).
†Possible subependymoma.