Table 3

Baseline patient characteristics of the included cluster randomised controlled trials studying patients with screen-detected and newly diagnosed diabetes

 Webb et al43Janssen et al39Griffin et al46Olivarius et al41
Follow-up duration (years)11115566
Type of diabetes patientsScreen-detected diabetesScreen-detected diabetesScreen-detected diabetesNewly diagnosed diabetes
CountryUKNetherlandsUK, Netherlands, DenmarkDenmark
Baseline patient characteristics
 Age (years)59.4±10.060.0±10.060.1±5.459.9±5.160.3±6.960.2±6.865.5 (55.3–74.0)65.3 (56.3–73.5)
 Sex (% men)56.958.351.856.058.557.352.453.1
 Ethnicity (% Caucasian)52.762.398.098.795.893.4
 Diabetes duration (years)00000000
 Current smoking (% yes)
 Body mass index (kg/m2)31.0±5.931.5±5.731.2±5.130.4±4.631.6±5.631.6±5.629.4 (26.2–33.0)28.8 (26.0–32.3)
 Systolic blood pressure (mm Hg)145.7±18.5148.4±20.5166±23163±23148.5±22.1149.8±21.3150 (130–164)148 (130–160)
 Diastolic blood pressure (mm Hg)87.8±10.489.5±10.790±1189±1086.1±11.186.5±11.385 (80–90)85 (80–90)
 UKPDS CHD risk (%)8.5±5.89.3±7.1*
 HbA1c (%)7.2±1.57.3±1.87.3±1.67.4±1.77.0±1.67.0±1.510.2 (8.6–11.6)10.2 (8.7–11.9)
 Total cholesterol (mmol/L)5.3±1.25.6±1.35.6±1.15.6±1.15.5±1.15.6±1.26.2 (5.4–7.1)6.2 (5.5–7.2)
 HDL-cholesterol (mmol/L)1.2±0.41.2±0.31.1±0.41.1±0.31.2 (1.0–1.5)1.2 (1.0–1.5)
 LDL-cholesterol (mmol/L)3.2±1.03.5±1.03.7±1.03.7±1.03.4±1.03.5±1.0
 Fasting glucose (mmol/L)7.8±2.38.1±2.813.8 (10.7–17.0)13.7 (10.7–17.0)
 Creatinine (μmol/L)83.4±17.184.9±18.690 (81–101)88 (79–100)
 Triglycerides (mmol/L)2.1±1.92.1±1.41.9±1.02.0±1.61.6 (1.2–2.3)1.7 (1.2–2.4)2.03 (1.44–2.91)1.98 (1.39–2.95)
 Urinary albumin (mg/L)11.7 (6.0–32.5)11.8 (5.7–27.5)
 Quality of life: PCS†39.0 (37.4–40.5)38.5 (37.1-40.0)No summary scores reported
 Quality of life: MCS†38.2 (35.2–41.2)39.2 (36.5–41.9)No summary scores reported
 History of myocardial infarction (%)15.8*10.6‡
 History of stroke (%)
 Diabetic retinopathy (%)5.04.5
 Peripheral neuropathy (%)18.819.7
  • Values are mean±sd, or median (IQR) or percentages. Bold font indicates that the comparison between the intervention and control group was statistically significant.

  • *Values concern the 5-year UKDPS CHD risk.

  • †Quality of life was assessed with the 12-item Short Form Health Survey (SF-12) in the study by Webb et al, and with the 36-item Short Form Health Survey (SF-36) in the study by Janssen et al.

  • ‡Defined as ‘pre-existing CVD’, including myocardial infarction, stroke and angina.

  • CHD, coronary heart disease; MCS, Mental Component Summary Score; PCS, Physical Component Summary Score; UKPDS, UK Prospective Diabetes Study.