No. of centres |
1 | 8 (5) | 29 (35) | 15 | 1–274 |
2–5 | 23 (15) | | | |
6–10 | 21 (14) | | | |
11–20 | 33 (22) | | | |
21–50 | 35 (23) | | | |
51–100 | 22 (15) | | | |
>100 | 5 (3) | | | |
Missing | 4 (3) | | | |
Original target recruitment |
≤200 | 14 (9) | 1231 (2946) | 545 | 90–28 000 |
201–400 | 40 (26) | | | |
401–600 | 31 (21) | | | |
601–800 | 15 (10) | | | |
>800 | 50 (33) | | | |
Missing | 1 (1) | | | |
Final target recruitment |
≤200 | 17 (11) | 1132 (2926) | 480 | 44–28 000 |
201–400 | 49 (32) | | | |
401–600 | 27 (18) | | | |
601–800 | 13 (9) | | | |
>800 | 45 (30) | | | |
Final total recruitment |
≤200 | 24 (16) | 1014 (2673) | 424 | 19–24 510 |
201–400 | 48 (32) | | | |
401–600 | 28 (19) | | | |
601–800 | 12 (8) | | | |
>800 | 39 (26) | | | |
Final recruitment target achieved |
Yes | 85 (56) | | | |
No, but with 80% of target | 119 (79) | | | |
No, <80% of target | 32 (21) | | | |
Timing of primary outcome follow-up (months postrandomisation) |
<1 month | 27 (18) | 9 (10) | 6 | 0–48 |
1–6 months | 54 (36) | | | |
6–18 months | 36 (24) | | | |
>18 months | 21 (14) | | | |
Missing | 13 (9) | | | |
Timing of final follow-up (months postrandomisation) |
<1 month | 9 (6) | 15 (18) | 12 | 0.066–120 |
1–6 months | 20 (13) | | | |
6–18 months | 84 (56) | | | |
>18 months | 33 (22) | | | |
Missing | 5 (3) | | | |