Total (n=510) | AKI (n=183) | Non-AKI (n=327) | p Value | |
---|---|---|---|---|
Age (year) | 57.94±18.85 | 64.47±15.31 | 54.29±19.67 | <0.001 |
Male | 245 (48.0%) | 97 (53.0%) | 148 (45.3%) | 0.097 |
HTN | 97 (19.0%) | 48 (26.2%) | 49 (15.0%) | 0.002 |
ARB use | 22 (4.3%) | 15 (8.2%) | 7 (2.1%) | 0.002 |
Diuretics use | 12 (2.4%) | 6 (3.3%) | 6 (1.8%) | 0.364 |
DM | 61 (12.0%) | 32 (17.5%) | 29 (8.9%) | 0.005 |
CKD | 27 (5.3%) | 19 (10.4%) | 8 (2.4%) | <0.001 |
Time to hospital presentation after Symptoms onset | 6.52±6.76 | 9.70±27.25 | 5.36±9.18 | 0.035 |
Symptoms and signs | ||||
Fever | 346 (85.0%) | 128 (87.1%) | 218 (83.8%) | 0.392 |
Myalgia | 102 (25.1%) | 32 (21.8%) | 70 (26.9%) | 0.284 |
General weakness | 48 (11.8%) | 14 (9.5%) | 34 (13.1%) | 0.338 |
Eschar | 200 (39.2%) | 80 (43.7%) | 120 (36.7%) | 0.131 |
WCC (x103/µL) | 7.16±3.54 | 7.56±3.77 | 6.92±3.39 | 0.055 |
Haemoglobin (g/dL) | 12.29±1.75 | 11.91±1.69 | 12.51±1.76 | 0.000 |
CRP (mg/L) | 49.91±54.27 | 56.16±62.53 | 46.04±48.17 | 0.072 |
HbA1c (%) | 7.59±2.35 | 8.10±2.42 | 6.87±2.07 | 0.033 |
Albumin (g/dL) | 3.45±0.60 | 3.19±0.61 | 3.60±0.55 | <0.001 |
AST (U/L) | 112.7±400.6 | 150.9±647.2 | 90.7±104.0 | 0.213 |
ALT (U/L) | 91.0±167.2 | 104.5±242.4 | 83.2±100.7 | 0.259 |
CK (IU/L) | 278.25±673.77 | 371.05±897.71 | 192.68±345.53 | 0.082 |
Creatinine (mg/dL) | 0.75±0.46 | 0.77±0.72 | 0.74±0.22 | 0.571 |
Haematuria | 179 (36.5%) | 80 (44.4%) | 99 (31.8%) | 0.005 |
Proteinuria | 159 (32.3%) | 73 (40.3%) | 86 (27.7%) | 0.005 |
Trace | 100 (62.9%) | 44 (60.3%) | 56 (65.1%) | 0.367 |
1+ | 43 (27.0%) | 20 (27.4%) | 23 (26.7%) | |
2+ | 11 (6.9%) | 6 (8.2%) | 5 (5.8%) | |
3+ | 5 (3.1%) | 3 (4.1%) | 2 (2.3%) | |
Tsutsugamushi Ab titre | 3234.04±5785.24 | 3762.6±3369.2 | 2862.2±6046.5 | 0.159 |
Hospital stay (days) | 6.92±18.01 | 9.70±27.25 | 5.36±9.18 | 0.039 |
CRRT | 3 (0.6%) | 3 (1.6%) | 0 (0.0%) | 0.045 |
Shock | 9 (1.8%) | 5 (2.7%) | 4 (1.2%) | 0.293 |
Admission to ICU | 8 (1.57%) | 8 (4.4%) | 0 (0.0%) | <0.001 |
Death | 4 (0.8%) | 4 (2.2%) | 0 (0.0%) | 0.016 |
Ab, antibody; AKI, acute kidney injury; ALT, alanine aminotransferase; ARB, angiotensin receptor blocker; AST, aspartate aminotransferase; CK, creatine kinase; CKD, chronic kidney disease; CRP, C reactive protein; CRRT, continuous renal replacement therapy; DM, diabetes mellitus; ESR, erythrocyte sedimentation rate; HbA1c, glycated haemoglobin; HTN, hypertension; ICU, intensive care unit; WCC, white cell count.