Clinical and laboratory data of AKI and non-AKI with CKD
| Total (n=27) | AKI (n=19) | Non-AKI (n=8) | p Value | |
|---|---|---|---|---|
| Age (year) | 72.59±10.52 | 73.95±9.03 | 69.38±13.58 | 0.311 |
| Male | 14 (51.9%) | 11 (57.9%) | 3 (37.5%) | 0.420 |
| HTN | 11 (40.7%) | 10 (52.6%) | 1 (12.5%) | 0.090 |
| ARB use | 3 (11.1%) | 3 (15.8%) | 0 (0.0%) | 0.532 |
| Diuretics use | 3 (11.1%) | 3 (15.8%) | 0 (0.0%) | 0.532 |
| DM | 9 (33.3%) | 7 (36.8%) | 2 (25.0%) | 0.676 |
| Time to hospital presentation after symptom (day) | 5.96±4.57 | 6.11±5.12 | 5.50±2.35 | 0.784 |
| Symptoms and signs | ||||
| Fever | 18 (75.0%) | 12 (70.6%) | 6 (85.7%) | 0.629 |
| Myalgia | 10 (41.7%) | 7 (41.2%) | 3 (42.9%) | 1.000 |
| General weakness | 3 (12.5%) | 2 (11.8%) | 1 (14.3%) | 1.000 |
| Eschar | 16 (59.3%) | 12 (63.2%) | 4 (50.0%) | 0.675 |
| WCC (x103/µL) | 8.39±4.20 | 8.16±4.75 | 8.95±2.64 | 0.664 |
| Haemoglobin (g/dL) | 11.01±1.51 | 10.74±1.44 | 11.68±1.56 | 0.144 |
| CRP (mg/L) | 83.18±73.52 | 82.24±80.14 | 85.19±62.02 | 0.928 |
| HbA1c (%) | 7.99±1.79 | 7.87±1.90 | 8.80 | 0.664 |
| Albumin (g/dL) | 3.10±0.62 | 3.01±0.67 | 3.31±0.48 | 0.258 |
| AST (U/L) | 411.44±1659.31 | 557.21±1975.12 | 65.25±23.43 | 0.493 |
| ALT (U/L) | 189.67±567.68 | 244.47±674.10 | 59.50±31.46 | 0.450 |
| eGFR (mL/min/1.73 m2) | 49.42±8.02 | 47.15±8.28 | 53.95±5.42 | 0.048 |
| Haematuria | 16 (59.3%) | 14 (73.7%) | 2 (25.0%) | 0.033 |
| Proteinuria | 15 (55.6%) | 12 (63.2%) | 3 (37.5%) | 0.398 |
| Trace | 4 (26.7%) | 3 (25.0%) | 1 (33.3%) | 0.891 |
| 1+ | 5 (33.3%) | 4 (33.3%) | 1 (33.3%) | |
| 2+ | 4 (26.7%) | 3 (25.0%) | 1 (33.3%) | |
| 3+ | 2 (13.3%) | 2 (16.7%) | 0 (0.0%) | |
| Tsutsugamushi Ab titre | 2725.71±3087.79 | 3080.00±3463.41 | 1840.00±1798.13 | 0.420 |
| Hospital stay (days) | 6.59±6.80 | 6.63±7.67 | 6.50±4.53 | 0.964 |
| CRRT | 2 (7.4%) | 2 (10.5%) | 0 (0.0%) | 0.567 |
| Shock | 3 (11.1%) | 2 (10.5%) | 1 (12.5%) | 1.000 |
| Admission to ICU | 3 (11.1%) | 3 (15.8%) | 0 (0.0%) | 0.532 |
| Death | 4 (14.8%) | 4 (21.1%) | 0 (0.0%) | 0.285 |
Ab, antibody; AKI, acute kidney injury; ALT, alanine aminotransferase; ARB, angiotensin receptor blocker; AST, aspartate aminotransferase; CK, creatine kinase; CKD, chronic kidney disease; CRP, C reactive protein; CRRT, continuous renal replacement therapy; DM, diabetes mellitus; eGFR, estimated glomerular filtration rate by the Modification of Diet in Renal Disease study (MDRD); ESR, erythrocyte sedimentation rate; HbA1c, glycated haemoglobin; HTN, hypertension; ICU, intensive care unit; WBC, white cell count.