I | II | III | |||||
---|---|---|---|---|---|---|---|
Tertile of serum 25(OH)D† N | 1592 | 1589 | 1577 | ||||
n or mean | % or 95% CI | n or mean | % or 95% CI | n or mean | % or 95% CI | p Value | |
Sex n % | |||||||
Males | 782 | 32.9 | 800 | 33.7 | 792 | 33.4 | 0.75 |
Females | 810 | 33.9 | 789 | 33.2 | 785 | 32.9 | |
Environmental factors | |||||||
Season of blood drawn‡ n % | |||||||
High sunlight | 566 | 19.2 | 1012 | 34.3 | 1375 | 46.5 | <0.0001 |
Low sunlight | 1026 | 56.9 | 577 | 31.9 | 202 | 11.2 | |
Latitude§ n % | |||||||
65°N | 210 | 23.6 | 305 | 34.2 | 376 | 42.2 | 0.0006 |
>65°N | 923 | 29.7 | 1042 | 33.6 | 1140 | 36.7 | |
Anthropometry | |||||||
Body mass index (kg/m2) mean 95% CI | 24.8 | 24.6 to 25.0 | 24.8 | 24.6 to 24.9 | 24.4 | 24.2 to 24.6 | 0.017 |
Waist circumference (cm) mean 95% CI | 84.6 | 83.9 to 85.2 | 84.0 | 83.4 to 84.6 | 82.9 | 82.3 to 83.4 | 0.0003 |
Socioeconomic position n % | |||||||
I+II (Professional) | 421 | 37.2 | 374 | 32.9 | 339 | 29.9 | 0.0046 |
III (Skilled worker) | 501 | 33.8 | 503 | 33.9 | 479 | 32.3 | |
IV (Unskilled worker) | 386 | 31.4 | 427 | 34.8 | 415 | 33.8 | |
V (Farmer) | 60 | 36.4 | 49 | 29.7 | 56 | 33.9 | |
VI (Other) | 224 | 29.9 | 236 | 31.6 | 288 | 38.5 | |
Lifestyle factors | |||||||
Smoking n % | |||||||
Non-smoker | 742 | 34.9 | 686 | 32.2 | 700 | 32.9 | 0.055 |
Former/occasional smoker | 366 | 30.2 | 438 | 36.1 | 410 | 33.7 | |
Active smoker | 484 | 34.2 | 465 | 32.9 | 467 | 32.9 | |
Alcohol consumption (g/day) n % | |||||||
Abstainer | 165 | 38.7 | 146 | 34.3 | 115 | 27.0 | 0.053 |
Low risk drinker | 1335 | 32.9 | 1349 | 33.3 | 1369 | 33.8 | |
At-risk drinker | 92 | 32.9 | 94 | 33.7 | 93 | 33.4 | |
Leisure time computer use n % | |||||||
Never | 537 | 31.4 | 599 | 35.1 | 572 | 33.5 | 0.0012 |
No more than once per week | 208 | 30.1 | 234 | 33.9 | 249 | 36.0 | |
On 2 to 5 days per week | 487 | 34.3 | 447 | 31.5 | 485 | 34.2 | |
On more than 5 days per week | 360 | 38.3 | 309 | 32.9 | 271 | 28.8 | |
Quartile of physical activity (MET hours per week) n % | |||||||
QI: 0.0–3.79 | 444 | 36.6 | 394 | 32.5 | 376 | 30.9 | <0.0001 |
QII: 3.80–11.29 | 403 | 33.9 | 421 | 35.4 | 365 | 30.7 | |
QIII: 11.30–21.99 | 415 | 34.5 | 397 | 33.0 | 391 | 32.5 | |
QIV: >22.0 | 330 | 28.7 | 377 | 32.7 | 445 | 38.6 | |
Diet score n % | |||||||
0–1 | 478 | 32.7 | 477 | 32.7 | 506 | 34.6 | 0.26 |
2–3 | 912 | 33.3 | 920 | 33.6 | 907 | 33.1 | |
4–5 | 202 | 36.2 | 192 | 34.4 | 164 | 29.4 | |
Females only | |||||||
Contraception n % | |||||||
No contraception | 441 | 38.2 | 401 | 34.8 | 312 | 27.0 | <0.001 |
Other kinds of contraception | 216 | 36.6 | 187 | 31.6 | 188 | 31.8 | |
Oral contraceptive pills | 140 | 23.1 | 190 | 31.3 | 277 | 45.6 |
The values are expressed as mean and 95% CIs; numbers and %.
*Differences between males and females were tested with ANOVA for normally distributed variables and Pearson's χ2 test for categorical variables.
†Mean (95% CI) of 25-hydroxyvitamin D tertiles for all were 41.50 (41.11 to 41.89), 63.87 (63.55 to 64.19) and 100.01 (98.81 to 101.22). Serum total 25(OH)D may differ slightly from the actual sum of D2 and D3 because of amendment of undetectable D2 values (see methods).
‡The season of blood sampling were categorised as high sunlight (summer (1 June–30 August), autumn (1 September–31 October)) and low sunlight (winter (1 November–31 March) and spring (1 April–31 May)).
§Data included only on samples taken during all seasons from Oulu city and other provinces of Oulu and Lapland. Data not included on N=343 in men and N=419 in women with samples taken during winter months from Helsinki region.
MET, metabolic equivalent of task of physical activity; 25(OH)D, 25-hydroxyvitamin D;