Baseline characteristics of patients with type A AAD onset in different seasons
| Characteristic | Winter (N=129) | Spring (N=147) | Summer (N=92) | Autumn (N=124) | p Value |
|---|---|---|---|---|---|
| Age, years | 48.7±11.8 | 47.7±11.0 | 48.6±13.0 | 48.1±12.2 | 0.90 |
| Male | 103 (78.9) | 123 (83.7) | 64 (69.6) | 108(87.2) | 0.01 |
| Hypertension | 97 (75.2) | 96 (65.3) | 68 (73.9) | 92(74.2) | 0.23 |
| Diabetes mellitus | 0 (0.0) | 5 (3.4) | 9 (9.8) | 2 (1.6) | <0.01 |
| Coronary artery disease | 6 (4.7) | 6 (4.1) | 8 (8.7) | 3 (2.4) | 0.21 |
| Smoker | 42 (37.8) | 61 (41.5) | 33 (35.9) | 44 (35.5) | 0.79 |
| Alcohol consumption | 27(20.9) | 36 (24.5) | 13 (14.1) | 23 (18.5) | 0.25 |
| Duration of pain, hours | 10.0 (4.0–24.0) | 12.0 (5.0–24.0) | 20.0 (5.0–24.0) | 19 (5.1–24.0) | 0.49 |
| SBP, mm Hg | 131.8±22.1 | 136.4±27.4 | 140.6±26.0 | 138.2±25.9 | 0.09 |
| DBP, mm Hg | 72.6±19.7 | 76.2±18.5 | 79.1±22.3 | 78.5±18.5 | 0.06 |
| Heart rate, beats/min | 84.7±16.3 | 85.3±16.5 | 81.4±14.2 | 83.0±15.0 | 0.24 |
| WBC count, ×109 cells/L | 9.7 (7.1–13.4) | 9.9 (7.6–12.5) | 9.4 (6.5–13.5) | 10.2 (7.9–14.1) | 0.48 |
| Platelet count, ×109 cells/L | 177 (144.0–236.5) | 175 (132.0–221.0) | 176 (140.0–233.0) | 200 (139.0–267.8) | 0.16 |
| C-reactive protein, mg/L | 8.0 (4.5–55.9) | 7.9 (3.91–46.4) | 5.8 (3.7–33.0) | 5.7 (3.7–46.9) | 0.06 |
| d-Dimer, mg/L | 3.3 (1.4–5.2) | 3.1 (1.3–5.7) | 3.8 (1.4–7.9) | 4.5 (2.1–9.2) | 0.10 |
| Serum creatinine, μmol/L | 90.9 (73.2–117.0) | 89.0 (74.0–115.0) | 86 (75.0–111.0) | 92.5 (74.9–127.3) | 0.57 |
| Ascending aorta diameter, mm | 44.7±10.0 | 47.0±10.9 | 44.6±13.4 | 45.7±11.5 | 0.30 |
| Treatment | |||||
| β-Blocker | 99 (76.7) | 119 (81.0) | 76 (82.6) | 96 (77.4) | 0.65 |
| CCB | 84 (65.1) | 114 (77.6) | 63 (68.5) | 59 (47.6) | <0.01 |
| ACEI | 67 (46.7) | 72 (48.2) | 40 (43.5) | 51 (41.1) | 0.30 |
| ARB | 19 (14.7) | 16 (10.9) | 11 (12.0) | 14 (11.3) | 0.78 |
| Surgical intervention | 80 (62.0) | 108 (73.5) | 70 (76.1) | 71 (57.3) | 0.01 |
Values are mean±SD, n (%) or median (IQR).
AAD, acute aortic dissection; ACEI, ACE inhibitor; ARB, angiotensin receptor blocker; CCB, calcium channel blocker; DBP, diastolic blood pressure; SBP, systolic blood pressure; WBC, white blood cell.