Secondary outcome measures possible randomised controlled trial by assessment time and study group
| Measures | Study group | Baseline Mean (SD) Median (IQR) | 6 weeks Mean (SD) Median (IQR) | 12 weeks Mean (SD) Median (IQR) | 24 weeks Mean (SD) Median (IQR) |
|---|---|---|---|---|---|
| Global fatigue score23 | Control | 36 (21.6) 31 (28.0) | 35 (22.0) 43 (37.0) | 32 (21.9) 26 (40.0) | 28 (24.5) 18 (47.5) |
| Intervention | 32 (22.3) 33 (43.0) | 18 (15.9) 15 (24.0) | 23 (17.3) 25 (33.0) | 29 (19.1) 31 (24.7) | |
| Cohen's d effect size (95% CI) | −0.18 (−0.78 to 0.43) | −0.89 (−1.61 to −0.11) | −0.45 (−1.20 to 0.32) | 0.04 (−0.78 to 0.87) | |
| Exercise self-efficacy24 | Control | 28 (6.0) 29 (9.0) | 29 (5.5) 29 (6.0) | 29 (4.6) 30 (6.0) | 29 (5.0) 28 (4.5) |
| Intervention | 30 (6.0) 31 (8.0) | 33 (5.2) 33 (10.0) | 33 (5.4) 36 (10.0) | 34 (4.6) 34 (8.25) | |
| Cohen's d effect size (95% CI) | 0.33 (−0.28 to 0.94) | 0.75 (−0.01 to 1.71) | 0.80 (−0.01 to 1.56) | 1.01 (0.10 to 1.84) | |
| Stress total score25 | Control | 9 (9.0) 6 (12.0) | 8 (9.1) 5 (9.5) | 4 (4.7) 4 (8.0) | 9 (9.5) 8 (0–26) |
| Intervention | 8 (9.7) 2 (18.0) | 4 (5.1) 4 (6.0) | 5 (5.9) 4 (10.0) | 3 (3.6) 2 (6.0) | |
| Cohen's d effect size (95% CI) | −0.11 (−0.71 to 0.50) | −0.54 (−1.26 to 0.20) | 0.19 (−0.57 to 0.94) | −0.76 (−1.59 to 0.11) | |
| Anxiety total score25 | Control | 6 (5.3) 6 (6.0) | 5 (5.4) 4 (6.5) | 3 (3.1) 2 (6.0) | 6 (8.3) 2 (9.0) |
| Intervention | 4 (7.1) 2 (4.0) | 2 (3.3) 0 (2.0) | 4 (6.0) 2 (4.0) | 2 (2.7) 0 (5.0) | |
| Cohen's d effect size (95% CI) | −0.32 (−0.92 to 0.30) | −0.67 (−1.39 to 0.08) | 0.21 (−0.55 to 0.96) | −0.60 (−1.42 to 0.26) | |
| Depression total score25 | Control | 8 (7.2) 6 (11.0) | 8 (8.4) 2 (14.0) | 5 (6.5) 2 (9.0) | 8 (9.0) 2 (13.0) |
| Intervention | 8 (10.1) 6 (15.0) | 3 (4.9) 0 (4.0) | 4 (5.9) 0 (6.0) | 4 (5.7) 2 (9.0) | |
| Cohen's d effect size (95% CI) | 0.00 (−0.60 to 0.60) | −0.73 (−1.43 to 0.03) | −0.16 (−0.91 to 0.60) | −0.52 (−1.33 to 0.34) | |
| EQ-5D score26 | Control | 2 (0.66) 2 (1.0) | 2 (0.5) 2 (1.0) | 2 (0.6) 1 (1.0) | 1 (0.5) 1 (0.7) |
| Intervention | 1 (0.52) 1 (1.0) | 1 (0.4) 1 (0.8) | 1 (0.4) 1 (1.0) | 1 (0.4) 1 (0.6) | |
| Cohen's d effect size (95% CI) | −1.68 (−2.35 to −0.95) | −2.21 (−3.05 to −1.25) | −1.95 (−2.80 to −0.98) | 0.00 (−0.82 to 0.82) | |
| EQ-VAS Your health today score out of 10026 | Control | 72 (22.6) 80 (40) | 82 (12.1) 78 (20.3) | 76 (26.4) 90 (41.5) | 79 (19.6) 80 (31.0) |
| Intervention | 75 (17.0) 70 (30) | 84 (12.8) 85 (20.0) | 78 (18.1) 80 (28.8) | 81 (14.9) 80 (25.0) | |
| Cohen's d effect size (95% CI) | 0.15 (−0.46 to 0.75) | 0.16 (−0.56 to 0.87) | 0.09 (−0.67 to 0.84) | 0.17 (−0.67 to 0.99) | |
| Active/moderately active27 | N (%) | N (%) | N (%) | N (%) | |
| Control | 2 (10) | 0 | 1 (7) | 0 | |
| Intervention | 6 (29) | 5 (34) | 4 (31) | 2 (20) | |
| Walked ≥3 hours in last 7 days27 | Control | 9 (47) | 7 (54) | 11 (79) | 9 (82) |
| Intervention | 9 (43) | 9 (70) | 7 (58) | 5 (62) |