Study | Challenge | Detail | Number approached | Number delivered to researcher | Number entered into study |
---|---|---|---|---|---|
SPIROA The Effect of Spironolactone on Pain in Older People with Osteoarthritis | Required data from both primary and secondary care | This study sought to recruit people with osteoarthritis and knee pain who had not been on NSAIDs, ACE inhibitors or spironolactone. They required eight additional participants before a 2-week deadline | 25 | 16 | 8 |
DIRECT DIabetes REmission Clinical Trial | Rescue before recruitment closure | This study required recently diagnosed people with diabetes within 3 weeks before study closure | 12 | 8 | 2 |
DECIDE Decision-making and comprehension of interactive and static Summary of Findings tables. | Large-scale survey | Complex survey exploring preferences for presentation of risk which had struggled to get responses. 20% response was desired. However, the survey was only compatible with desktop operating systems and therefore was inaccessible to the large numbers of registrants who clicked through from mobile devices. | 50 000 | 16 266 viewed full email, 9183 clicked and attempted survey | Over 2000 completed. |
H. PYLORI Infection And Acid Secretory Function | Anticipated high refusal rate | Study which required 150 healthy volunteers willing to undergo endoscopy | 1400 | 251 | 150 |
REFORM— | Finding people with multiple morbidity | Research into the Effect Of SGLT2 inhibition on left ventricular remodelling in patients with heart failure and diabetes mellitus | 63 | 27 | 15 |
NSAIDs, non-steroidal anti-inflammatory drugs.