Stress resilience in adolescence and subsequent Crohn's disease risk in adulthood at least 4 years after the conscription assessment
| Stress resilience | Events/n | Unadjusted HR (95% CI) | Adjusted* HR (95% CI) |
|---|---|---|---|
| Main analysis | |||
| Low | 225/50 965 | 1.54 (1.26 to 1.88) | 1.39 (1.13 to 1.71) |
| Moderate | 547/130 994 | 1.43 (1.20 to 1.70) | 1.36 (1.14 to 1.62) |
| High | 166/57 632 | Reference | Reference |
| Sensitivity analysis — excluding those with elevated ESR, low EVF and underweight | |||
| Low | 115/41 735 | 1.53 (1.23 to 1.91) | 1.45 (1.16 to 1.81) |
| Moderate | 301/113 417 | 1.34 (1.11 to 1.62) | 1.32 (1.09 to 1.59) |
| High | 101/53 007 | Reference | Reference |
| Sensitivity analysis — follow-up at least 15 years after the conscription assessment | |||
| Low | 147/49 278 | 1.46 (1.15 to 1.87) | 1.37 (1.07 to 1.75) |
| Moderate | 377/127 750 | 1.42 (1.16 to 1.76) | 1.39 (1.22 to 1.71) |
| High | 114/55 644 | Reference | Reference |
*Adjusted for BMI, ESR, EVF, height, parental SEI, appendicitis before age 20 and region of residence.
BMI, body mass index; ESR, erythrocyte sedimentation rate; EVF, erythrocyte volume fraction; n, number; SEI, socioeconomic index.