Coronary revascularisation | Drug therapy | ||||||||
---|---|---|---|---|---|---|---|---|---|
Cohort* | IHD | Size | Men | Women | Aspirin | ACE inhibitors | β-blockers | Statins | Ca-channel blockers† |
Age 60 | No | 11 964 | 0 (0%) | 0 (0%) | 271 (2%) | 678 (6%) | 1156 (10%) | 208 (2%) | 615 (5%) |
Angina | 594 | 97 (19%) | 7 (8%) | 211 (36%) | 95 (16%) | 238 (40%) | 148 (25%) | 264 (44%) | |
Single AMI | 3465 | 486 (18%) | 77 (11%) | 1467 (42%) | 768 (22%) | 1482 (43%) | 951 (27%) | 1080 (31%) | |
Multiple AMIs | 721 | 194 (32%) | 20 (18%) | 386 (54%) | 256 (36%) | 314 (44%) | 247 (34%) | 290 (40%) | |
Age 65 | No | 30 201 | 0 (0%) | 0 (0%) | 2548 (8%) | 3299 (11%) | 3727 (12%) | 2194 (7%) | 2709 (9%) |
Angina | 2445 | 512 (25%) | 30 (7%) | 1400 (57%) | 701 (29%) | 1036 (42%) | 1164 (48%) | 1024 (42%) | |
Single AMI | 8796 | 1532 (23%) | 334 (16%) | 5751 (65%) | 3452 (39%) | 4011 (46%) | 4722 (54%) | 2762 (31%) | |
Multiple AMIs | 2086 | 594 (35%) | 67 (17%) | 1532 (73%) | 1072 (51%) | 946 (45%) | 1272 (61%) | 722 (35%) | |
Age 70 | No | 49 768 | 0 (0%) | 0 (0%) | 8698 (17%) | 9756 (20%) | 7176 (14%) | 8863 (18%) | 6820 (14%) |
Angina | 5528 | 1263 (28%) | 125 (12%) | 3851 (70%) | 2204 (40%) | 2376 (43%) | 3335 (60%) | 2235 (40%) | |
Single AMI | 14 847 | 2811 (26%) | 730 (18%) | 11 269 (76%) | 7770 (52%) | 6989 (47%) | 9638 (65%) | 4461 (30%) | |
Multiple AMIs | 3585 | 1012 (36%) | 172 (22%) | 2918 (81%) | 2202 (61%) | 1721 (48%) | 2524 (70%) | 1219 (34%) | |
Age 75 | No | 49 822 | 0 (0%) | 0 (0%) | 12 592 (25%) | 12 633 (25%) | 7945 (16%) | 11 318 (23%) | 8574 (17%) |
Angina | 7472 | 1652 (29%) | 225 (13%) | 5642 (76%) | 3430 (46%) | 3188 (43%) | 4780 (64%) | 2952 (40%) | |
Single AMI | 15 319 | 2705 (26%) | 835 (17%) | 12 487 (82%) | 9226 (60%) | 7036 (46%) | 10 395 (68%) | 4676 (31%) | |
Multiple AMIs | 3779 | 954 (35%) | 230 (23%) | 3295 (87%) | 2574 (68%) | 1759 (47%) | 2767 (73%) | 1228 (32%) |
*The age cohorts included cases with history of AMI who were matched to three controls on sex, year of birth category, and general practice. The prevalence of treatment by the initial ages was affected by calendar year (see online supplementary figure SA2).
†First-line drugs prescription until 2007 after which it became a second-line drugs prescription.2
AMI, acute myocardial infarction; IHD, ischaemic heart disease.