Table 1

Assumptions and calculations of target prices

MedicineDasatinibGefitinib
Daily dose100 mg250 mg
Tablets per month2828
API price per kilogram£1841.14£802.56
API cost per tablet£0.18£0.20
Add cost of excipients£0.19£0.21
Add cost of tableting£0.22£0.24
Cost per month£6.06£6.61
Add cost of bottle, packaging, shipping, duties£6.29£6.84
Add 50% mark-up£9.43£10.26
Target price per year£122.95£133.73
  • The prices of excipients used for each TKI are given in text, but not shown in table. Bold values are the final target price.

  • EGFR, Epidermal growth factor receptor; TKI, tyrosine kinase inhibitor.