Table 4

Incremental cost-effectiveness measures (within trial analysis)

Probability cost-effective at Rc
DataInterventionCost (£)ΔCost (£)QALYΔQALYICER (ΔCost/ ΔQALY) (£)£20 000£30 000
Complete case*Standard care14869812.5330.06914 2840.6710.776
Lens extraction24672.602
Multiple imputationStandard care15678442.4420.10084300.8850.940
Lens extraction24112.542
  • *179 of 285 (93 (64.14%) in the lens extraction and 86 (61.43%) in the standard care group) UK participants have complete cost and QALY data—above regression results are based on the data of these complete cases.

  • ICER, incremental cost-effectiveness ratio; QALY, quality-adjusted life years; Rc, ceiling ratio of willingness to pay per QALY gained.