Proportion of new users of ACE inhibitors or angiotensin receptor blockers who continue or discontinue treatment according to guideline recommended cut-off levels of serum creatinine and potassium at follow-up testing*
| Continuation† | Discontinuation† | Total | |
|---|---|---|---|
| Total number, % | 42 942 (93.1) | 3178 (6.9) | 46 120 (100) |
| Serum creatinine increase ≥30%, n (%) | 462 (81.5) | 105 (18.5) | 567 (100) |
| Serum potassium >6 mmol/L, n (%) | 150 (78.5) | 41 (21.5) | 191 (100) |
*Calculated from the most recent measurements within 1 month before and 2 months after drug initiation.
†A patient was considered a continuous user when the end date of the first continuous course of therapy was larger than the date of the first follow-up monitoring +30 days (to allow for stockpiling and irregular use).