Characteristics of hospital admissions for pneumonia as primary diagnosis in patients without type 2 diabetes in Spain, 2004–2013
| 2004 | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | Total | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| N | 56 991 | 66 996 | 58 233 | 66 504 | 67 123 | 74 338 | 67 643 | 72 762 | 74 816 | 72 015 | 677 421 |
| Incidence* (per 100 000 inhabitants) | 316.24 | 355.18 | 295.55 | 337.53 | 333.66 | 362.07 | 329.46 | 348.43 | 358.27 | 341.98 | 338.21 |
| Women, n (%)* | 20 375 (35.75) | 24 955 (37.25) | 21 500 (36.92) | 25 263 (37.99) | 26 195 (39.03) | 29 742 (40.01) | 26 715 (39.49) | 29 407 (40.42) | 30 912 (41.32) | 29 455 (40.9) | 264 519 (39.05) |
| Age, mean (SD) | 73.96 (13.25) | 74.26 (13.36) | 74.24 (13.64) | 74.33 (13.78) | 74.79 (13.78) | 73.77 (14.61) | 75.67 (13.72) | 75.65 (13.86) | 77.02 (13.28) | 76.36 (13.73) | 75.06 (13.76) |
| 40–64 years, n (%)† | 12 471 (21.88) | 14 327 (21.38) | 13 036 (22.39) | 15 012 (22.57) | 14 768 (22) | 18 992 (25.55) | 13 930 (20.59) | 15 392 (21.15) | 13 497 (18.04) | 14 306 (19.87) | 145 731 (21.51) |
| 65–74 years, n (%)† | 12 578 (22.07) | 14 150 (21.12) | 11 555 (19.84) | 12 535 (18.85) | 12 153 (18.11) | 12 409 (16.69) | 11 068 (16.36) | 11 581 (15.92) | 11 321 (15.13) | 10 965 (15.23) | 120 315 (17.76) |
| 75–84 years, n (%)† | 19 395 (34.03) | 23 171 (34.59) | 19 755 (33.92) | 22 482 (33.81) | 22 213 (33.09) | 23 189 (31.19) | 22 555 (33.34) | 23 706 (32.58) | 24 640 (32.93) | 23 151 (32.15) | 224 257 (33.1) |
| ≥85 years, n (%)* | 12 547 (22.02) | 15 348 (22.91) | 13 887 (23.85) | 16 475 (24.77) | 17 989 (26.8) | 19 748 (26.57) | 20 090 (29.7) | 22 083 (30.35) | 25 358 (33.89) | 23 593 (32.76) | 187 118 (27.62) |
| AMI, n (%)* | 1932 (3.39) | 2309 (3.45) | 1917 (3.29) | 2279 (3.43) | 2123 (3.16) | 2207 (2.97) | 1884 (2.79) | 1955 (2.69) | 1952 (2.61) | 1802 (2.5) | 20 360 (3.01) |
| CHF, n (%)* | 6649 (11.67) | 7929 (11.84) | 6761 (11.61) | 8228 (12.37) | 8673 (12.92) | 9310 (12.52) | 9516 (14.07) | 10 896 (14.97) | 12 004 (16.04) | 11 680 (16.22) | 91 646 (13.53) |
| PVD, n (%)* | 1857 (3.26) | 2345 (3.5) | 2121 (3.64) | 2239 (3.37) | 2237 (3.33) | 2445 (3.29) | 2496 (3.69) | 2753 (3.78) | 2923 (3.91) | 3074 (4.27) | 24 490 (3.62) |
| CEVD/HP/PAPL, n (%)* | 3993 (7.01) | 4543 (6.78) | 4020 (6.9) | 4505 (6.77) | 4969 (7.4) | 5487 (7.38) | 5561 (8.22) | 6088 (8.37) | 6508 (8.7) | 6322 (8.78) | 51 996 (7.68) |
| Chronic pulmonary disease, n (%)† | 20 012 (35.11) | 23 065 (34.43) | 19 416 (33.34) | 21 961 (33.02) | 21 810 (32.49) | 24 120 (32.45) | 22 753 (33.64) | 24 112 (33.14) | 24 376 (32.58) | 23 789 (33.03) | 225 414 (33.28) |
| Dementia, n (%)* | 5402 (9.48) | 6295 (9.4) | 5833 (10.02) | 6224 (9.36) | 6904 (10.29) | 7599 (10.22) | 7793 (11.52) | 8536 (11.73) | 9300 (12.43) | 8742 (12.14) | 72 628 (10.72) |
| Renal disease, n (%)* | 4363 (7.66) | 5327 (7.95) | 4609 (7.91) | 5760 (8.66) | 6328 (9.43) | 7189 (9.67) | 7312 (10.81) | 8278 (11.38) | 9609 (12.84) | 9572 (13.29) | 68 347 (10.09) |
| Any type of malignancy, n (%)* | 5696 (9.99) | 6420 (9.58) | 6006 (10.31) | 6671 (10.03) | 6929 (10.32) | 7642 (10.28) | 7504 (11.09) | 8234 (11.32) | 8289 (11.08) | 8407 (11.67) | 71 798 (10.6) |
| Any liver disease, n (%) | 2825 (4.96) | 3362 (5.02) | 2942 (5.05) | 3436 (5.17) | 3409 (5.08) | 3852 (5.18) | 3457 (5.11) | 3689 (5.07) | 3733 (4.99) | 3754 (5.21) | 34 459 (5.09) |
| Obesity, n (%)* | 1940 (3.4) | 2352 (3.51) | 2044 (3.51) | 2304 (3.46) | 2489 (3.71) | 3188 (4.29) | 2839 (4.2) | 3367 (4.63) | 3393 (4.54) | 3529 (4.9) | 27 445 (4.05) |
| Pleuritis, n (%)* | 3992 (7) | 4898 (7.31) | 4240 (7.28) | 4936 (7.42) | 4760 (7.09) | 4892 (6.58) | 4782 (7.07) | 4954 (6.81) | 5054 (6.76) | 5101 (7.08) | 47 609 (7.03) |
| CCI 0, n (%)† | 18 620 (32.67) | 22 311 (33.3) | 19 452 (33.4) | 22 643 (34.05) | 21 991 (32.76) | 24 786 (33.34) | 20 436 (30.21) | 21 691 (29.81) | 21 653 (28.94) | 20 550 (28.54) | 214 133 (31.61) |
| CCI 1, n (%)* | 28 219 (49.51) | 32 726 (48.85) | 28 327 (48.64) | 31 765 (47.76) | 32 752 (48.79) | 35 890 (48.28) | 33 399 (49.38) | 36 155 (49.69) | 37 205 (49.73) | 35 850 (49.78) | 332 288 (49.05) |
| CCI≥2, n (%)* | 10 152 (17.81) | 11 959 (17.85) | 10 454 (17.95) | 12 096 (18.19) | 12 380 (18.44) | 13 662 (18.38) | 13 808 (20.41) | 14 916 (20.5) | 15 958 (21.33) | 15 615 (21.68) | 131 000 (19.34) |
| CAT, n (%)* | 5936 (10.42) | 6931 (10.35) | 6565 (11.27) | 8042 (12.09) | 8487 (12.64) | 9356 (12.59) | 9191 (13.59) | 9690 (13.32) | 9627 (12.87) | 10 028 (13.92) | 83 853 (12.38) |
| Bronchial fibroscopy, n (%)† | 2165 (3.8) | 2256 (3.37) | 2068 (3.55) | 2245 (3.38) | 2220 (3.31) | 2258 (3.04) | 2135 (3.16) | 2207 (3.03) | 2195 (2.93) | 2351 (3.26) | 22 100 (3.26) |
| Non-invasive MV, n (%)* | 442 (0.78) | 584 (0.87) | 531 (0.91) | 718 (1.08) | 945 (1.41) | 1188 (1.6) | 1616 (2.39) | 1934 (2.66) | 2307 (3.08) | 2286 (3.17) | 12 551 (1.85) |
| Invasive MV, n (%)† | 1426 (2.5) | 1700 (2.54) | 1140 (1.96) | 1338 (2.01) | 1405 (2.09) | 1520 (2.04) | 1279 (1.89) | 1516 (2.08) | 1336 (1.79) | 1287 (1.79) | 13 947 (2.06) |
| Thoracocentesis, n (%)* | 1271 (2.23) | 1476 (2.2) | 1308 (2.25) | 1527 (2.3) | 1549 (2.31) | 1655 (2.23) | 1502 (2.22) | 1508 (2.07) | 1518 (2.03) | 1636 (2.27) | 14 950 (2.21) |
| Red cell transfusion, n (%)* | 1830 (3.21) | 2125 (3.17) | 2034 (3.49) | 2189 (3.29) | 2498 (3.72) | 2642 (3.55) | 2709 (4) | 2830 (3.89) | 3073 (4.11) | 3009 (4.18) | 24 939 (3.68) |
| Readmission, n (%)* | 6633 (11.64) | 7830 (11.69) | 7063 (12.13) | 7889 (11.86) | 8121 (12.1) | 8947 (12.04) | 8794 (13) | 9515 (13.08) | 10 427 (13.94) | 9716 (13.49) | 84 935 (12.54) |
| LOHS, median (IQR) | 8 (5–13) | 8 (5–13) | 8 (5–12) | 8 (5–12) | 8 (5–12) | 7 (4–12) | 7 (5–12) | 7 (4–11) | 7 (4–11) | 7 (4–11) | 7 (5–12) |
| IHM, n (%)† | 8036 (14.1) | 9900 (14.78) | 8121 (13.95) | 8758 (13.17) | 9105 (13.56) | 9727 (13.08) | 9087 (13.43) | 10 209 (14.03) | 10 777 (14.4) | 9803 (13.61) | 93 523 (13.81) |
| Streptococcus pneumoniae, n (%)† | 9736 (17.08) | 11 685 (17.44) | 10 295 (17.68) | 12 295 (18.49) | 11 899 (17.73) | 12 099 (16.28) | 10 081 (14.9) | 7147 (9.82) | 5918 (7.91) | 6101 (8.47) | 97 256 (14.36) |
| Legionella, n (%)† | 667 (1.17) | 808 (1.21) | 727 (1.25) | 667 (1) | 678 (1.01) | 729 (0.98) | 668 (0.99) | 544 (0.75) | 546 (0.73) | 449 (0.62) | 6483 (0.96) |
| Staphylococcus aureus, n (%)* | 253 (0.44) | 350 (0.52) | 286 (0.49) | 366 (0.55) | 368 (0.55) | 378 (0.51) | 400 (0.59) | 438 (0.6) | 503 (0.67) | 470 (0.65) | 3812 (0.56) |
| Haemophilus influenzae, n (%) | 267 (0.47) | 272 (0.41) | 257 (0.44) | 264 (0.4) | 263 (0.39) | 293 (0.39) | 295 (0.44) | 289 (0.4) | 300 (0.4) | 333 (0.46) | 2833 (0.42) |
| Pseudomonas aeruginosa, n (%) | 509 (0.89) | 597 (0.89) | 514 (0.88) | 574 (0.86) | 617 (0.92) | 622 (0.84) | 632 (0.93) | 632 (0.87) | 638 (0.85) | 685 (0.95) | 6020 (0.89) |
Incidence was adjusted by age and sex.
*p<0.05 to assess increased time trend from 2004 to 2013.
†p<0.05 to assess decreased time trend from 2004 to 2013.
AMI, acute myocardial infarction; CAT, computerised axial tomography of thorax; CCI, Charlson Comorbidity Index; CEVD/HP/PAPL, cerebrovascular disease/hemiplegia/paraplegia; CHF, congestive heart failure; IHM, in-hospital mortality; LOHS, length of hospital stay; MV, mechanical ventilation; PVD, peripheral vascular disease.