Standard care and additional to standard care procedures
| Procedure | Timing | Dose, frequency and/or duration |
|---|---|---|
| Standard care | ||
| Appendicectomy laparoscopic or open | During admission | Once only |
| Preoperative antibiotic | During admission | Once only |
| Postoperative antibiotic | During admission and/or after discharge | As clinically indicated |
| Follow-up visit | 4 to 6 weeks after discharge | Once only |
| Additional to standard care | ||
| Intravenous piperacillin with tazobactam | During admission | 100 mg/kg/dose every 8 hours for at least 24 hours up to 48 hours |
| Appendicectomy laparoscopic or open | During admission when patient failed to respond to antibiotic therapy | None, or once only |
| Oral amoxicillin plus clavulanic acid | On discharge | 22.5 mg/kg/dose twice per day to complete a total 7-day course of antibiotics |
| Oral ciprofloxacin and metronidazole | On discharge for patient allergic to augmentin | 15 mg/kg/dose two times per day, and 10 mg/kg/dose two times per day, respectively, to complete a total 7-day course of antibiotics |
| Telephone interview | 1, 2 weeks, 3, 6 and 12 months after discharge | 5–10 min each interview. 5 times in total |