Twenty-four-hour ambulatory blood pressure
| Blood pressure (mm Hg) | MD of enalapril | BD of enalapril | Mean difference (95% CL) | p Value |
|---|---|---|---|---|
| Daytime SBP | 132.6±2.7 | 133.8±2.3 | 1.2 (−2.8 to 5.2) | 0.56 |
| Daytime DBP | 72.8±1.5 | 73.1±1.5 | 0.4 (−1.3 to 2.1) | 0.64 |
| Daytime MAP | 93.7±1.6 | 94.1±1.4 | 0.5 (−2.2 to 3.1) | 0.74 |
| Night-time SBP | 121.1±2.6 | 119.1±2.7 | −2.1 (−5.0 to 0.7) | 0.14 |
| Night-time DBP | 63.7±1.3 | 62.7±1.2 | −1.0 (−2.7 to 0.7) | 0.23 |
| Night-time MAP | 84.7±1.5 | 83.0±1.5 | −1.7 (−3.6 to 0.2) | 0.07 |
| Daytime PP | 59.9±1.8 | 60.8±1.8 | 0.9 (−1.5 to 3.4) | 0.46 |
| Night-time PP | 57.4±1.9 | 56.4±2.0 | −1.0 (−2.7 to 0.7) | 0.25 |
| Daytime HR | 72.0±1.6 | 73.0±1.6 | 0.9 (−0.4 to 2.1) | 0.15 |
| Night-time HR | 66.3±1.3 | 65.5±1.4 | −0.8 (2.5 to 0.9) | 0.34 |
| Dipping (%) | ||||
| SBP dipping | 8.6±1.2 | 11.0±1.6 | 2.4 (0.03 to 4.9) | 0.048a |
| DBP dipping | 12.3±1.2 | 13.9±1.5 | 1.7 (−0.7 to 4.1) | 0.17 |
| MAP dipping | 9.5±1.2 | 11.7±1.5 | 2.2 (−0.1 to 4.5) | 0.07 |
Daytime is defined as 7:01 to 23:00 and night-time as 23:01 to 7:00.
Data are mean±SEM.
SBP, DBP, MAP and PP are measured in mm Hg. Dipping is in per cent.
ap Value <0.05.
BD, bedtime dosing; CL, confidence limits; DBP, diastolic blood pressure; HR, heart rate; MAP, mean arterial pressure; MD, morning dosing; PP, pulse pressure; SBP, systolic blood pressure.