Table 1

Overview of the two training interventions

HRTMIT
ExercisesLeg-press, chest-press, knee-extensions, low rowing, leg-curl, ankle plantar flexion, hip-abduction.
Abdominal crunches and lower back exercises*
Squats, push-ups, seated knee-extensions, seated low rowing, standing hip-abduction and hip-extension, heel raises.
Abdominal crunches and lower back exercises*
EquipmentExercise machines (Technogym, Cesena, Italy)Elastic exercise bands, 30 and 90 cm loops (Thera Band, Akron, Ohio, USA). Own body weight.
Intensity6–12 rep (∼70–85% of 1RM†)10–18 rep (∼50–60% of 1RM†)
Rest between sets1–2 minCircuit training: All exercises are performed once and the ‘circuit’ is repeated three times. No rest between exercises
Contraction velocity2 s concentric, 2 s eccentric2 s concentric 2 s eccentric except for push-ups, squats and heel raises that are 1 s concentric and 3 s eccentric
Acclimatisation6–8 weeks
Week 1: 1 set of 15 rep
Week 2: 2 sets of 15 rep
Week 3–8: 3 sets of 15 rep
6–8 weeks
Week 1: 1 round of 10 rep
Week 2: 2 rounds of 10 rep
Week 3–8: 3 rounds of 10–18 rep
ProgressionFrom week 7–9:
Periodisation regimen:
2 weeks of 3×12 rep (∼70% 1RM)
2 weeks of 3×10 rep (∼75% 1RM)
2 weeks of 3×8 rep (∼80% 1RM)
2 weeks of 3×6 rep (∼85% 1RM)
1 week of restitution
The period is repeated.
Training load is increased when the individual can do more repetitions than the number specified in the training protocol above
From week 7–9:
3 rounds of 10–18 rep. A gradual increase from 3 rounds of 10 to 3 rounds of 18 rep. The last rep should feel exhaustive. Training load increases by using a stronger elastic band (red → green → blue → black → silver → gold) except for (1) push-ups where load increases by gradually decreasing the angle of the body relative to the floor, (2) squats where load increases by putting one foot on a stool (5–10 cm high) and thereby gradually loading the foot on the floor more and (3) heel raises where load increases by changing from a bilateral to unilateral performance and finally by using weight vests (adding 5–10% of the body weight) in (1), (2) and (3).
OrganisationGroups of 4Groups of 8
LocationPrivate fitness centre (paid by the project)Hospital once a week
At home two times a week
SupervisionThree times weeklyOnce a week
At home two times a week.
  • *Abdominal crunches and lower back exercises are included in the training programme to strengthen the core region. Three sets of 15 repetitions are performed at the end of each training session. They do not follow the periodisation regimen, but difficulty is continuously adjusted by skilled physical trainers.

  • †A 1RM test is not performed but relative intensity in % 1RM is estimated according to Brzycki.69 Participants are told that the last repetitions should feel exhaustive.

  • HRT, heavy resistance training; MIT, moderate intensity training; Rep, repetitions; RM, repetition maximum; S, seconds.