Positive predictive values of cardiovascular diagnoses in the Danish National Patient Registry, by type of diagnosis
| Primary diagnosis | Secondary diagnosis | Inpatient diagnosis | Outpatient diagnosis | |||||
|---|---|---|---|---|---|---|---|---|
| Confirmed diagnoses/available records | Positive predictive value, % (95% CI) | Confirmed diagnoses/available records | Positive predictive value, % (95% CI) | Confirmed diagnoses/available records | Positive predictive value, % (95% CI) | Confirmed diagnoses/available records | Positive predictive value, % (95% CI) | |
| Myocardial infarction | ||||||||
| First-time myocardial infarction | 88/89 | 99 (94 to 100) | 8/10 | 80 (49 to 94) | – | – | – | – |
| Recurrent myocardial infarction | 88/100 | 88 (80 to 93) | 0/0 | – | – | – | – | – |
| Stent thrombosis | 14/15 | 93 (70 to 99) | 8/9 | 89 (57 to 98) | – | – | – | – |
| Angina pectoris | ||||||||
| Stable angina pectoris | 68/73 | 93 (85 to 97) | 21/23 | 91 (73 to 98) | – | – | – | – |
| Unstable angina pectoris | 80/90 | 89 (81 to 94) | 4/6 | 67 (30 to 90) | – | – | – | – |
| Heart failure | ||||||||
| First-time heart failure | 31/39 | 79 (64 to 89) | 41/56 | 73 (60 to 83) | – | – | – | – |
| Readmission for heart failure | 73/96 | 76 (67 to 83) | 0/0 | – | – | – | – | – |
| Cardiomyopathy | ||||||||
| Cardiomyopathy overall | 56/61 | 92 (82 to 96) | 24/37 | 65 (49 to 78) | 34/41 | 83 (69 to 91) | 26/27 | 96 (82 to 99) |
| Dilated cardiomyopathy | 8/10 | 80 (49 to 94) | 7/10 | 70 (40 to 89) | 11/15 | 73 (48 to 89) | 4/5 | 80 (38 to 96) |
| Hypertrophic cardiomyopathy | 11/12 | 92 (65 to 99) | 7/8 | 88 (53 to 98) | 8/10 | 80 (49 to 94) | 10/10 | 100 (72 to 100) |
| Restrictive cardiomyopathy | 6/8 | 75 (41 to 93) | 1/1 | 100 (21 to 100) | 7/8 | 88 (53 to 98) | 0/1 | 0 (0 to 79) |
| Arrhythmogenic right ventricular cardiomyopathy | 11/11 | 100 (74 to 100) | 9/9 | 100 (70 to 100) | 8/8 | 100 (68 to 100) | 12/12 | 100 (76 to 100) |
| Takotsubo cardiomyopathy | 20/20 | 100 (84 to 100) | 0/0 | – | – | – | – | – |
| Hypertension | ||||||||
| Arterial hypertension | 30/33 | 91 (76 to 97) | 59/64 | 92 (83 to 97) | 49/53 | 92 (82 to 97) | 40/44 | 91 (79 to 96) |
| Pulmonary hypertension | 54/61 | 89 (78 to 94) | 33/39 | 85 (70 to 93) | 58/60 | 97 (89 to 99) | 29/40 | 73 (57 to 84) |
| Cardiac arrhythmias | ||||||||
| Atrial fibrillation or flutter | 55/58 | 95 (86 to 98) | 37/39 | 95 (83 to 99) | 75/75 | 100 (95 to 100) | 17/22 | 77 (57 to 90) |
| Bradycardia | 75/79 | 95 (88 to 98) | 12/21 | 57 (37 to 76) | 78/85 | 92 (84 to 96) | 9/15 | 60 (36 to 80) |
| Ventricular tachycardia or fibrillation | 46/58 | 79 (67 to 88) | 31/38 | 82 (67 to 91) | 70/77 | 91 (82 to 96) | 7/19 | 37 (19 to 59) |
| Cardiac arrest | 66/67 | 99 (92 to 100) | 28/33 | 85 (69 to 93) | – | – | – | – |
| Valvular heart disease | ||||||||
| Mitral regurgitation or stenosis | 19/20 | 95 (76 to 99) | 28/29 | 97 (83 to 99) | 21/21 | 100 (85 to 100) | 26/28 | 93 (77 to 98) |
| Aortic regurgitation or stenosis | 29/30 | 97 (83 to 99) | 20/20 | 100 (84 to 100) | 31/31 | 100 (89 to 100) | 18/19 | 95 (75 to 99) |
| Inflammation/infection | ||||||||
| Endocarditis | 73/86 | 85 (76 to 91) | 6/10 | 60 (31 to 83) | 75/90 | 83 (74 to 90) | 4/6 | 67 (30 to 90) |
| Myocarditis | 33/41 | 80 (66 to 90) | 9/25 | 36 (20 to 55) | 37/59 | 63 (50 to 74) | 5/7 | 71 (36 to 92) |
| Pericarditis | 76/82 | 93 (85 to 97) | 14/16 | 88 (64 to 97) | 74/76 | 97 (91 to 99) | 16/22 | 73 (52 to 87) |
| Aortic diseases | ||||||||
| Aortic dissection | 45/48 | 94 (83 to 98) | 1/2 | 50 (9 to 91) | – | – | – | – |
| Aortic aneurysm/dilation | 37/37 | 100 (91 to 100) | 13/13 | 100 (77 to 100) | 20/20 | 100 (84 to 100) | 30/30 | 100 (89 to 100) |
| Venous thromboembolism | ||||||||
| First-time venous thromboembolism | 76/84 | 90 (82 to 95) | 11/15 | 73 (48 to 89) | 81/90 | 90 (82 to 95) | 6/9 | 67 (35 to 88) |
| First-time deep venous thrombosis | 38/44 | 86 (73 to 94) | 5/6 | 83 (44 to 97) | 38/43 | 88 (76 to 95) | 5/7 | 71 (36 to 92) |
| First-time pulmonary embolism | 38/40 | 95 (84 to 99) | 6/9 | 67 (35 to 88) | 43/47 | 91 (80 to 97) | 1/2 | 50 (9 to 91) |
| Recurrent venous thromboembolism | 65/77 | 84 (75 to 91) | 2/16 | 13 (4 to 36) | – | – | – | – |
| Recurrent deep venous thrombosis | 29/36 | 81 (65 to 90) | 0/3 | 0 (0 to 56) | – | – | – | – |
| Recurrent pulmonary embolism | 36/41 | 88 (74 to 95) | 2/13 | 15 (4 to 42) | – | – | – | – |
| Other | ||||||||
| Arterial claudication | 83/92 | 90 (82 to 44) | 5/5 | 100 (57 to 100) | 15/17 | 88 (66 to 97) | 73/80 | 91 (83 to 96) |
| Hypercholesterolaemia | 17/17 | 100 (82 to 100) | 73/77 | 95 (87 to 98) | 62/64 | 97 (89 to 99) | 28/30 | 93 (79 to 98) |
| Cardiac tumours | 16/18 | 89 (67 to 97) | 6/8 | 75 (41 to 93) | 19/23 | 83 (63 to 93) | 3/3 | 100 (44 to 100) |