Variables used in predictive modelling
| Variable | Categories |
|---|---|
| Total cholesterol | <5.0, 5.0–6.9, ≥7.0 |
| TC/HDL ratio | ≤1.2, 1.3–1.4, 1.5–1.7, ≥1.8 |
| Prior cholesterol measurements | 0, 1–2, 3–4, ≥5 |
| Calculated QRISK2 | <10%, 10–14.9%, 15–19.9%, ≥20% |
| Coded QRISK2 | <10%, 10–14.9%, 15–19.9%, ≥20%, missing |
| Systolic BP | <140, 140–159, ≥160, missing |
| Age | 40–49, 50–59, 60–69, ≥70 |
| Sex | Male, female |
| Ethnicity | White, Asian, black, other, missing |
| Townsend deprivation quintile | 1st, 2nd, 3rd, 4th, 5th, missing |
| Urban/rural score | Urban, rural, missing |
| BMI | <20, 20–24.9, 25–29.9, 30–34.9, 35+, missing |
| Smoking status | Current smoker, ex-smoker, non-smoker, missing |
| Liver transaminases | Normal, abnormal, missing |
| Diabetes mellitus | Yes, no |
| Family history of CVD | Yes, no |
| Atrial fibrillation | Yes, no |
| Rheumatoid arthritis | Yes, no |
| Hypertension | Yes, no |
| Chronic kidney disease | Yes, no |
| HIV | Yes, no |
| Severe enduring mental illness* | Yes, no |
| Inflammatory conditions† | Yes, no |
| Antipsychotic medication | Yes, no |
| Long-term corticosteroids | Yes, no |
| Immunosuppressant medication | Yes, no |
| Year quartile | 1st, 2nd, 3rd, 4th |
*Schizophrenia, bipolar affective disorder, mania or psychosis (unspecified), psychotic depression.
†Systemic lupus erythematosus, scleroderma, Bechet's syndrome, other inflammatory arthritis.
BMI, body mass index; BP, blood pressure; CVD, cardiovascular disease; HDL, high-density lipoprotein.