Comparisons of clinical variables between participants with and without EO by gender
| M (n=7110) | F (n=4842) | |||||
|---|---|---|---|---|---|---|
| Clinical variables | EO (n=1438) | non-EO (n=5739) | p Value | EO (n=484) | non-EO (n=4429) | p Value |
| Age (years) | 49.5±11.9 | 48.4±13.0 | 0.002 | 49.4±13.0 | 49.0±13.1 | 0.452 |
| BMI (kg/m2) | 25.6±3.3 | 24.9±3.2 | <0.001 | 23.9±3.9 | 23.3±3.7 | 0.004 |
| General obesity | 398 (27.9) | 1325 (23.3) | <0.001 | 91 (19.1) | 637 (14.6) | 0.009 |
| Waist circumference (cm) | 89.5±8.7 | 87.6±8.7 | <0.001 | 78.3±9.7 | 77.0±9.3 | 0.005 |
| Central obesity | 660 (46.3) | 2222 (39.1) | <0.001 | 182 (38.2) | 1474 (33.8) | 0.055 |
| Systolic blood pressure (mm Hg) | 123.2±16.6 | 122.0±15.9 | 0.014 | 115.2±19.4 | 113.7±17.9 | 0.100 |
| Diastolic blood pressure (mm Hg) | 73.8±10.5 | 73.8±10.1 | 0.858 | 66.2±10.5 | 65.8±10.1 | 0.347 |
| Fasting plasma glucose (mmol/L) | 5.41±1.63 | 5.36±1.49 | 0.264 | 5.18±1.50 | 5.16±1.30 | 0.726 |
| 2-hour postload glucose (mmol/L) | 7.32±3.19 | 6.96±3.11 | <0.001 | 6.86±2.74 | 6.72±2.77 | 0.315 |
| Glycated haemoglobin (%) | 5.92±1.14 | 5.81±1.01 | 0.002 | 5.78±0.95 | 5.74±0.91 | 0.350 |
| Aspartate aminotransferase (IU/L) | 27.2±17.7 | 26.7±14.0 | 0.232 | 23.2±10.1 | 23.1±11.0 | 0.895 |
| Alanine aminotransferase (IU/L) | 35.8±24.4 | 34.8±25.3 | 0.161 | 23.6±15.4 | 23.1±17.7 | 0.659 |
| Creatinine (µmol/L) | 88.8±51.6 | 88.8±40.0 | 1.000 | 64.5±23.0 | 63.6±17.7 | 0.345 |
| eGFR (mL/min/1.73 m2) | 95.9±26.1 | 94.2±26.0 | 0.035 | 105.5±31.1 | 104.0±28.4 | 0.310 |
| Total cholesterol (mmol/L) | 5.15±0.95 | 5.14±0.97 | 0.893 | 5.13±0.99 | 5.14±0.99 | 0.858 |
| Triglyceride (mmol/L) | 1.82±1.23 | 1.72±1.22 | 0.003 | 1.28±0.91 | 1.24±0.78 | 0.303 |
| HDL-C (mmol/L) | 1.12±0.29 | 1.16±0.30 | <0.001 | 1.42±0.38 | 1.43±0.36 | 0.558 |
| Hypertriglyceridaemia (≥1.69 mmol/L) | 631 (44.2) | 2093 (36.8) | <0.001 | 97 (20.3) | 792 (18.1) | 0.241 |
| Low HDL-C (F<1.29, M<1.03 mmol/L) | 609 (42.7) | 2027 (35.7) | <0.001 | 188 (39.4) | 1648 (37.8) | 0.497 |
| Diabetes mellitus | 251 (17.6) | 838 (14.7) | 0.008 | 69 (14.5) | 546 (12.5) | 0.223 |
| Hypertension | 320 (22.4) | 1241 (21.8) | 0.632 | 95 (19.9) | 725 (16.6) | 0.068 |
| Metabolic syndrome | 421 (29.5) | 1273 (22.4) | <0.001 | 99 (20.8) | 734 (16.8) | 0.030 |
| NAFLD | 405 (28.4) | 1434 (25.2) | 0.015 | 173 (36.3) | 1184 (27.1) | <0.001 |
| Hiatal hernia | 209 (14.6) | 48 (0.8) | <0.001 | 65 (13.6) | 10 (0.2) | <0.001 |
| Alcohol consumption | 11 (0.8) | 37 (0.7) | 0.621 | |||
| Tea drinking | 555 (38.9) | 2002 (35.2) | 0.010 | 121 (25.4) | 1187 (27.2) | 0.394 |
| Smoking | 268 (18.8) | 918 (16.2) | 0.017 | 9 (1.9) | 85 (1.9) | 0.928 |
| Habitual exercise | 155 (10.9) | 504 (8.9) | 0.020 | 26 (5.5) | 245 (5.6) | 0.884 |
Data are shown as the mean±SD or number (%).
BMI, body mass index; eGFR, estimated glomerular filtration rate; EO, erosive oesophagitis; F, female; HDL-C, high-density lipoprotein cholesterol; M, male; NAFLD, non-alcoholic fatty liver disease.