Unadjusted | Adjusted† | ||||||
---|---|---|---|---|---|---|---|
Characteristics | Number | Per cent | In-hospital mortality | OR (95% CI) | p Value | OR (95% CI) | p Value |
Overall | 3741 | – | 550 (14.7%) | – | – | – | – |
Age, year | <0.001* | <0.001 | |||||
<60 | 1006 | 26.9 | 74 (7.4) | 1 | 1 | ||
60–69 | 899 | 24.0 | 108 (12.0) | 1.72 (1.26 to 2.35) | 1.68 (1.20 to 2.36) | ||
70–79 | 1236 | 33.0 | 218 (17.6) | 2.70 (2.04 to 3.56) | 2.49 (1.83 to 3.39) | ||
≥80 | 600 | 16.0 | 150 (25.0) | 4.20 (3.11 to 5.67) | 3.72 (2.66 to 5.20) | ||
Female | 1281 | 34.2 | 264 (20.6) | 1.97 (1.64 to 2.37) | <0.001 | 1.65 (1.34 to 2.02) | <0.001 |
History of CHD | 0.4 | ||||||
None | 2835 | 75.8 | 417 (14.7) | 1 | |||
Prior CHD, but no MI | 460 | 12.3 | 75 (16.3) | 1.13 (0.86 to 1.48) | |||
Prior MI | 446 | 11.9 | 58 (13.0) | 0.87 (0.65 to 1.16) | |||
Prior PCI | 59 | 1.6 | 5 (8.5) | 0.53 (0.21 to 1.34) | 0.2 | ||
History of diabetes | 591 | 15.8 | 107 (18.1) | 1.35 (1.07 to 1.70) | 0.01 | 1.44 (1.12 to 1.87) | 0.005 |
History of hypertension | 1756 | 46.9 | 239 (13.6) | 0.85 (0.71 to 1.02) | 0.08 | ||
History of stroke | 450 | 12.0 | 78 (17.3) | 1.25 (0.96 to 1.63) | 0.09 | ||
History of chronic lung disease | 186 | 5.0 | 29 (15.6) | 1.08 (0.72 to 1.62) | 0.7 | ||
Chest discomfort | 2654 | 70.9 | 334 (12.6) | 0.58 (0.48 to 0.70) | <0.001 | 0.80 (0.65 to 0.98) | 0.03 |
Other ischaemic symptom | 1430 | 38.2 | 174 (12.2) | 0.71 (0.59 to 0.86) | 0.001 | ||
Time from symptom to admission, hour | 0.001* | ||||||
<3 | 835 | 22.3 | 152 (18.2) | 1 | |||
3–5 | 781 | 20.9 | 113 (14.5) | 0.76 (0.58 to 0.99) | |||
6–11 | 739 | 19.8 | 99 (13.4) | 0.70 (0.53 to 0.92) | |||
12–24 | 1386 | 37.0 | 186 (13.4) | 0.70 (0.55 to 0.88) | |||
Cardiac arrest at presentation | 51 | 1.4 | 20 (39.2) | 3.85 (2.18 to 6.80) | <0.001 | 2.51 (1.29 to 4.89) | 0.007 |
SBP at admission, mm Hg | <0.001* | <0.001 | |||||
<80 | 142 | 3.8 | 89 (62.7) | – | 1 | ||
80–99 | 377 | 10.1 | 107 (28.4) | 0.24 (0.16 to 0.35) | 0.26 (0.17 to 0.41) | ||
100–119 | 816 | 21.8 | 111 (13.6) | 0.09 (0.06 to 0.14) | 0.11 (0.07 to 0.17) | ||
120–139 | 1063 | 28.4 | 120 (11.2) | 0.08 (0.05 to 0.11) | 0.08 (0.05 to 0.12) | ||
≥140 | 1343 | 35.9 | 123 (9.2) | 0.06 (0.04 to 0.09) | 0.06 (0.04 to 0.09) | ||
Respiration rate at admission >20 bpm | 977 | 26.1 | 195 (20.0) | 1.69 (1.40 to 2.05) | <0.001 | ||
Heart rate at admission, bpm | <0.001* | <0.001 | |||||
≤50 | 245 | 6.5 | 56 (22.9) | 2.31 (1.68 to 3.18) | 1.39 (0.95 to 2.01) | ||
51–99 | 2863 | 76.5 | 326 (11.4) | 1 | 1 | ||
≥100 | 633 | 16.9 | 168 (26.5) | 2.81 (2.28 to 3.47) | 2.14 (1.70 to 2.71) | ||
Infarct location | |||||||
Anterior‡ | 1732 | 46.3 | 308 (17.8) | 1.58 (1.32 to 1.90) | <0.001 | 1.70 (1.38 to 2.11) | <0.001 |
Inferior | 1395 | 37.3 | 195 (14.0) | 0.91 (0.75 to 1.10) | 0.3 | ||
Posterior or right ventricular | 466 | 12.5 | 81 (17.4) | 1.26 (0.97 to 1.63) | 0.08 | 1.46 (1.09 to 1.96) | 0.01 |
Left bundle branch block | 70 | 1.9 | 19 (27.1) | 2.20 (1.29 to 3.76) | 0.004 |
*p Value for trend.
†The c-statistics of the final logistic model is 0.77.
‡Including anterior, extensive anterior, anteroseptal or lateral infarction.
CHD, coronary heart disease; MI, myocardial infarction; PCI, percutaneous coronary intervention; SBP, systolic blood pressure.