Table 1

Weighted seroprevalence of HSV1 and HSV2 by selected characteristics in adult men (N=5227) and women (N=4441) aged 20–49 years, NHANES 1999–2012

HSV1HSV2
MenWomenMenWomen
CharacteristicsPer centp ValuePer centp ValuePer centp ValuePer centp Value
Overall56.9%60.2%12.2%24.5%
Anthropometrics
Obesity (BMI≥30 kg/m2)
 No55.0%0.00257.7%<0.00112.1%0.89221.9%<0.001
 Yes61.2%65.5%12.3%29.8%
Abdominal obesity (WC>88 or 102 cm)
 No54.8%0.00155.2%<0.00112.0%0.60819.2%<0.001
 Yes60.8%64.6%12.5%29.1%
BMI category (kg/m2)
 18.5–24.953.8%0.00354.6%<0.00112.1%0.93418.1%<0.001
 25–29.955.9%62.2%12.2%27.6%
 30–34.961.3%66.0%12.7%28.2%
 ≥3561.2%65.0%11.5%31.3%
Demographics
Race
 Non-Hispanic white51.2%<0.00154.0%<0.0019.5%<0.00119.0%<0.001
 Non-Hispanic black61.0%68.1%33.6%57.3%
 Mexican American and others74.1%77.4%11.6%23.7%
Education ≥ college
 No61.4%<0.00164.6%<0.00113.7%<0.00128.4%<0.001
 Yes45.1%49.6%8.1%15.0%
Marital status
 Married59.7%0.00261.1%0.09311.1%0.02420.3%<0.001
 Single or divorced53.3%57.9%12.5%30.4%
 Living with a partner53.9%63.8%16.5%26.3%
Annual household income level
 PIR<2.563.1%<0.00166.4%<0.00114.2%0.00129.4%<0.001
 PIR≥2.552.6%55.2%10.8%20.5%
Coverage by health insurance
 No63.8%<0.00168.7%<0.00115.8%<0.00127.9%0.025
 Yes54.3%58.1%10.9%23.6%
Risk factors
Hypertension historyn=5195n=4426n=5195n=4426
 No55.7%0.00658.9%<0.00112.0%0.48923.2%0.002
 Yes61.7%68.0%13.0%31.3%
Diabetes historyn=5192n=4406n=5192n=4406
 No56.7%0.35259.5%<0.00112.0%0.02824.1%0.007
 Yes61.3%80.0%17.5%36.0%
≥12 drinks in past 12 monthsn=5224n=4436n=5224n=4436
 No60.4%0.14665.6%<0.0018.8%0.00924.0%0.730
 Yes56.4%58.4%12.6%24.7%
Lifetime smoking ≥100 pieces
 No53.9%<0.00157.9%0.0049.7%<0.00119.4%<0.001
 Yes59.9%63.5%14.7%31.4%
Lifetime sex partners ≥5
 No50.9%<0.00159.4%0.4015.7%<0.00114.8%<0.001
 Yes59.8%60.9%15.4%32.1%
Recent sex partners ≥5 in prior 12 months
 No56.8%0.52060.3%0.50611.6%<0.00124.3%0.139
 Yes59.3%56.8%22.2%32.3%
Ever having genital herpes
 No57.0%0.54761.0%0.00210.8%<0.00121.3%<0.001
 Yes53.5%48.2%74.4%74.4%
Sex debut before age 16n=5222n=4436n=5222n=4436
 No61.7%<0.00163.9%0.01118.2%<0.00133.0%<0.001
 Yes54.6%58.8%9.4%21.1%
Using condomn=3561n=2951n=3561n=2951
 Not always54.8%0.73259.5%0.14414.1%0.39728.2%0.050
 Always55.8%54.8%12.6%22.7%
  • BMI, body mass index; HSV, herpes simplex virus; PIR, poverty index ratio; WC, waist circumference.