First offer: HPV self-sampling Arm A | First offer: Pap test Arm B | |||||||
---|---|---|---|---|---|---|---|---|
Number of potentially eligible women | Women screened | Number of potentially eligible women | Women screened | |||||
Type of analysis, primary outcome | N | Per cent‡ | N | Per cent‡ | Per cent difference between arms (95% CI)* | p Value† | ||
ITT analysis | ||||||||
Uptake in response to initial offer of screening§ | 404 | 54 | 20.0 (13.4) | 598 | 35 | 14.3 (5.9) | 5.7 (−11.6 to 34.0) | 0.628 |
Cumulative uptake§ | 404 | 55 | 20.6 (13.6) | 598 | 41 | 16.0 (6.9) | 4.6 (−13.9 to 32.3) | 0.694 |
Per protocol analysis | ||||||||
Uptake in response to initial offer of screening§ | 404 | 63 | 22.9 (15.6) | 430 | 26 | 10.6 (6.0) | 12.3 (2.4 to 46.6) | 0.305 |
Cumulative uptake§ | 404 | 63 | 22.9 (15.6) | 430 | 33 | 14.1 (7.7) | 8.8 (−4.7 to 39.6) | 0.448 |
*Percentage point difference between community-averaged uptake within each arm, CI was calculated by the bootstrap method.36
†p Value from permutation test.
‡The community-averaged uptake within each arm; the mean uptake within each arm are in in parentheses.
§Intracluster correlation coefficients (ICC) were calculated to be ∼0.01 for screening outcomes.