NEWS as a mortality predictor compared to the PSI and CURB-65 scores
| Mortality 30 days | Mortality 180 days | Mortality 6 years | |
|---|---|---|---|
| Unadjusted OR | 1.16 (1.07 to 1.27), p=0.001 | 1.13 (1.06 to 1.20), p<0.001 | 1.13 (95% CI 1.08 to 1.17), p<0.001 |
| Adjusted OR (model 1)* | 1.15 (1.05 to 1.25), p=0.003 | 1.11 (1.04 to 1.18), p=0.002 | 1.10 (95% CI 1.05 to 1.16), p<0.001 |
| Adjusted OR (model 2)† | 1.10 (1.01 to 1.21), p=0.035 | 1.07 (1.00 to 1.15), p=0.038 | 1.08 (95% CI 1.02 to 1.13), p=0.007 |
| Discrimination | |||
| AUC NEWS | 0.65 (0.58 to 0.72) | 0.62 (0.57 to 0.67) | 0.60 (95% CI 0.57 to 0.64) |
| AUC PSI | 0.80 (0.76 to 0.84) | 0.76 (0.72 to 0.80) | 0.79 (95% CI 0.76 to 0.81) |
| NEWS vs PSI | p<0.001 | p<0.001 | p<0.001 |
| AUC NEWS and PSI | 0.82 (0.77 to 0.86) | 0.77 (0.73 to 0.81) | 0.79 (95% CI 0.76 to 0.82) |
| NEWS and PSI vs PSI | p=0.084 | p=0.074 | p=0.911 |
| AUC CURB-65 | 0.72 (0.65 to 0.78) | 0.69 (0.64 to 0.74) | 0.73 (95% CI 0.69 to 0.76) |
| NEWS vs CURB-65 | p=0.076 | p=0.015 | p<0.001 |
| AUC NEWS and CURB-65 | 0.73 (0.67 to 0.79) | 0.70 (0.66 to 0.75) | 0.73 (95% CI 0.70 to 0.76) |
| NEWS and CURB-65 vs CURB-65 | p=0.178 | p=0.091 | p=0.29 |
Data from univariate and multivariate analysis are given as OR (95% CI) per point increase, p value. Data from the ROC analysis are given as AUC (95% CI) or p value.
*Adjusted for age, gender.
†Adjusted for age, gender, comorbidities (COPD, congestive heart failure, neoplastic disease, diabetes mellitus, coronary artery disease, cerebrovascular disease, PAOD, chronic renal failure).
AUC, area under the curve; CURB-65: confusion, urea >7 mmol/L−1, respiratory frequency ≥30 breaths/min−1, low blood pressure (systolic value <90 mm Hg or diastolic value ≤60 mm Hg) and age ≥65 years; NEWS, National Early Warning Score; PSI, pneumonia severity index.